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Ethylene Glycol and Propylene Glycol Toxicity
Table of Contents

Course: WB 1103
CE Original Date: October 3, 2007
CE Renewal Date: October 3, 2010
CE Expiration Date: October 3, 2012
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Cover Page Key Concepts About This and Other Case Studies in Environmental Medicine How to Apply for and Receive Continuing Education Credit Accreditation Council for Continuing Medical Education (ACCME^®) American Nurses Credentialing Center (ANCC), Commission on Accreditation National Commission for Health Education Credentialing, Inc. (NCHEC) International Association for Continuing Education and Training (IACET) Acknowledgments Disclaimer and Disclosure	What Are the Physiological Effects of Ethylene Glycol Poisoning? Learning Objectives Introduction Neurologic Effects Possible Sequelae Cranial Nerve Damage Respiratory Effects Cardiovascular Effects Metabolic Effects Renal Effects Carcinogenicity and Teratogenicity Other Effects Key Points Progress Check
How to Use This Course Introduction Available Versions Instructions Instructional Format Learning Objectives	How Should Patients Exposed to Ethylene Glycol Be Evaluated? Learning Objectives Introduction Exposure History Physical Examination Clinical Presentation Key Points Progress Check
Initial Check Instructions Case Study, First Patient Case Study, Second Patient Initial Check Questions Initial Check Answers	What Laboratory Tests Can Help In Evaluating Patients Exposed to Ethylene Glycol? Learning Objectives Introduction Ethanol, Methanol, Ketoacidosis Urinary Crystals Urine Fluorescence Serum Analysis False Positives Glycolic Acid Analysis Anion and Osmolal Gaps Key Points Progress Check
What is Ethylene Glycol? Learning Objectives Definition Synonyms Toxicity Properties Uses Environmental Fate Key Points Progress Check	How Should Patients Exposed to Ethylene Glycol Be Treated? Learning Objectives Introduction First Steps Prevent Absorption Specific Treatment Monitor the Patient Calculate the Dose Monitor the Dose Fomepizole Treatment Guidelines Advantages of Fomepizole Treatment Disadvantages of Ethanol Treatment Hemodialysis Vitamin Treatment Key Points Progress Check
Where Is Ethylene Glycol Found? Learning Objectives Introduction Commercial Products Environmental Exposures Occupational Exposures Key Points Progress Check	What is Propylene Glycol? Learning Objectives Introduction Uses Concentrations in Food Use in Textiles Synonyms Special Uses De-Icing Sources of Exposure Who is at Risk? Biological Fate Physiological Effects Central Nervous System Effects Metabolic Effects Examples of Propylene Glycol Poisoning Phenytoin and Propylene Glycol Lack of Renal Effects Contact Dermatitis Comparison with Ethylene Glycol Clinical Presentation Treatment Standards and Regulations Key Points Progress Check
How Are People Exposed to Ethylene Glycol? Learning Objectives Introduction Dermal Exposure Inhalation Exposure Ingestion Who Is at Risk of Exposure? Exposure at Home Key Points Progress Check	What Instructions Should Be Given to Patients? Learning Objectives Introduction Self Care Clinical Follow-Up Key Points Progress Check
What Are the U.S. Standards for Ethylene Glycol Exposure Levels? Learning Objectives Introduction Workplace Environment Key Points Progress Check	Where Can I Find More Information? For More Information Other CSEMs
What Is the Biological Fate of Ethylene Glycol? Learning Objectives Introduction Rapid Transformation Metabolism in the Liver The Role of Alcohol Dehydrogenase Fomepizole Key Points Progress Check	Assessment and Posttest Instructions Introduction Online Instructions Posttest Relevant Content
What Are the Stages of Ethylene Glycol Intoxication? Learning Objectives Introduction Mechanism of Toxicity Stages of Ethylene Glycol Intoxication Key Points Progress Check	Literature Cited References

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Page last reviewed: December 10, 2013
Page last updated: October 3, 2007
Content source: Agency for Toxic Substances and Disease Registry

Agency for Toxic Substances and Disease Registry, 4770 Buford Hwy NE, Atlanta, GA 30341
Contact CDC: 800-232-4636 / TTY: 888-232-6348

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