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Toxicological Profile for 1,1-Dichloroethane
CAS#: 75-34-3
Toxicological Profile Information
The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties. Other pertinent literature is also presented, but is described in less detail than the key studies. The complete list of topics covered (chapter titles) is shown at the left and in more detail further down this page.
The focus of the profile is on health and toxicologic information.
Therefore, each profile begins with a Public Health Statement that summarizes in nontechnical
language, a substance's relevant properties.
A useful two page information sheet, the ToxFAQâ„¢, is also available.
In order to access the ATSDR toxicological profiles' PDF files below, you must have Adobe Acrobat Reader .
You may download that program for free from this link to Adobe and then use it to access (open) the files below that are labeled as PDF files.
The table of contents and list of individual PDF files are given below.
- Foreword
- Contributors
- Peer review
- Contents
- List of figures
- List of tables
1. Public Health Statement, 123 KB
- Overview
- A closer look at 1,1-dichloroethane
- How 1,1-dichloroethane can affect your health
- Children and 1,1-dichloroethane
- Medical tests to determine 1,1-dichloroethane exposure
- Federal government recommendations to protect human health
- Additional information
2. Relevance to Public Health, 64 KB
- 2.1 Background and environmental exposures to 1,1-dichloroethane in the united states
2.2 Summary of health effects
2.3 Minimal risk levels (MRLs)
- 3.1 Introduction
3.2 Discussion of health effects by route of exposure
3.3 Genotoxicity
3.4 Toxicokinetics
3.5 Mechanisms of action
3.6 Toxicities mediated through the neuroendocrine axis
3.7 Children's susceptibility
3.8 Biomarkers of exposure and effect
3.9 Interactions with other chemicals
3.10 Populations that are unusually susceptible
3.11 Methods for reducing toxic effects
3.12 Adequacy of the database
4. Chemical and Physical Information, 43 KB
- 4.1 Chemical identity
4.2 Physical and chemical properties
5. Production, Import/Export, Use, and Disposal, 44 KB
- 5.1 Production
5.2 Import/export
5.3 Use
5.4 Disposal
6. Potential for Human Exposure, 261 KB
- 6.1 Overview
6.2 Releases to the environment
6.3 Environmental fate
6.4 Levels monitored or estimated in the environment
6.5 General population and occupational exposure
6.6 Exposures of children
6.7 Populations with potentially high exposures
6.8 Adequacy of the database
- 7.1 Biological materials
7.2 Environmental samples
7.3 Adequacy of the database
8. Regulations, Advisories and Guidelines, 286 KB
- A. Minimal risk level worksheets
B. User's guide
C. Acronyms, abbreviations, and symbols
D. Index
Reference
Agency for Toxic Substances and Disease Registry (ATSDR). 2013. Toxicological profile for 1,1-Dichloroethane. (Draft for Public Comment) Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service.
Disclaimer
All ATSDR toxicological profile PDF files are electronic conversions from paper copy or other electronic ASCII text files. This conversion may have resulted in character translation or format errors. Users are referred to the original paper copy of the toxicological profile for the official text, figures, and tables. Original paper copies can be obtained via the directions on the toxicological profile home page, which also contains other important information about the profiles.
Where can I get more information?
If you have questions or concerns, please contact your community or state health or environmental quality department or:
For more information, contact:
Agency for Toxic Substances and Disease Registry
Division of Toxicology and Human Health Sciences
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Atlanta, GA 30329-4027
Phone: 1-800-CDC-INFO · 888-232-6348 (TTY)
Email: Contact CDC-INFO
ATSDR can also tell you the location of occupational and environmental health clinics. These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances.
Information line and technical assistance:
Phone: 888-422-8737
To order toxicological profiles, contact:
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5285 Port Royal Road
Springfield, VA 22161
Phone: 800-553-6847 or 703-605-6000
Disclaimer
Some PDF files may be electronic conversions from paper copy or other electronic ASCII text files. This conversion may have resulted in character translation or format errors. Users are referred to the original paper copy of the toxicological profile for the official text, figures, and tables. Original paper copies can be obtained via the directions on the toxicological profile home page, which also contains other important information about the profiles.
The information contained here was correct at the time of publication. Please check with the appropriate agency for any changes to the regulations or guidelines cited.
- Page last reviewed: January 21, 2015
- Page last updated: January 21, 2015
- Content source: Agency for Toxic Substances and Disease Registry