Toxicological Profile for n-Nitrosodimethylamine

CAS#: 62-75-9

PDF Version, 1.7 MB

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Toxicological Profile Information

The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties. Other pertinent literature is also presented, but is described in less detail than the key studies. The complete list of topics covered (chapter titles) is shown at the left and in more detail further down this page.

The focus of the profile is on health and toxicologic information. Therefore, each profile begins with a Public Health Statement that summarizes in nontechnical language, a substance's relevant properties.

A useful two page information sheet, the ToxFAQs^TM, is also available.

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Toxicological Profile Access

In order to access the ATSDR toxicological profiles' PDF files below, you must have Adobe Acrobat Reader.

You may download that program for free from this link to Adobe and then use it to access (open) the files below that are labeled as PDF files.

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Complete Profile, 1.7 MB

The table of contents and list of individual PDF files are given below.

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Preface, 331 KB

• Foreword
• List of figures
• List of tables

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1. Public Health Statement, 163 KB

1.1 What is this substance?
1.2 How might I be exposed to it?
1.3 How can it enter and leave my body?
1.4 How can it affect my health?
1.5 Is there a medical test to determine whether I have been exposed to it?
1.6 What levels of exposure have resulted in harmful health effects
1.7 What recommendations has the federal government made to protect human health?
1.8 Where can I get more information?

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2. Health Effects, 764 KB

2.1 Introduction
2.2 Discussion of health effects by route of exposure
2.3 Relevance to public health
2.4 Levels in human tissues and fluids associated with health effects
2.5 Levels in the environment associated with levels in human tissue and / or health effects
2.6 Toxicokinetics
2.7 Interactions with other chemicals
2.8 Populations that are unusually susceptible
2.9 Adequacy of the database

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3. Chemical and Physical Information, 116 KB

3.1 Chemical Identity
3.2 Physical and Chemical Properties

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4. Production, Import, Use, and Disposal, 19 KB

4.1 Production
4.2 Import
4.3 Use
4.4 Disposal

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5. Potential for Human Exposure, 94 KB

5.1 Overview
5.2 Releases to the environment
5.3 Environmental fate
5.4 Levels monitored or estimated in the environment
5.5 General population and occupational exposure
5.6 Populations with potentially high exposure
5.7 Adequacy of the database

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6. Analytical Methods, 160 KB

6.1 Biological materials
6.2 Environmental samples
6.3 Adequacy of the database

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7. Regulations and Advisories, 76 KB

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8. References, 55 KB

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9. Glossary, 15 KB

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Appendix, 19 KB

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Reference

Agency for Toxic Substances and Disease Registry (ATSDR). 1989. Toxicological profile for n-Nitrosodimethylamine. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service.

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Disclaimer

All ATSDR toxicological profile PDF files are electronic conversions from paper copy or other electronic ASCII text files. This conversion may have resulted in character translation or format errors. Users are referred to the original paper copy of the toxicological profile for the official text, figures, and tables. Original paper copies can be obtained via the directions on the toxicological profile home page, which also contains other important information about the profiles.

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Where can I get more information?

If you have questions or concerns, please contact your community or state health or environmental quality department or:

For more information, contact:
Agency for Toxic Substances and Disease Registry
Division of Toxicology and Human Health Sciences
1600 Clifton Road NE, Mailstop F-57
Atlanta, GA 30329-4027
Phone: 1-800-CDC-INFO · 888-232-6348 (TTY)
Email: Contact CDC-INFO

ATSDR can also tell you the location of occupational and environmental health clinics. These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances.

Information line and technical assistance:
Phone: 888-422-8737

To order toxicological profiles, contact:
National Technical Information Service
5285 Port Royal Road
Springfield, VA 22161
Phone: 800-553-6847 or 703-605-6000

Disclaimer
Some PDF files may be electronic conversions from paper copy or other electronic ASCII text files. This conversion may have resulted in character translation or format errors. Users are referred to the original paper copy of the toxicological profile for the official text, figures, and tables. Original paper copies can be obtained via the directions on the toxicological profile home page, which also contains other important information about the profiles.

The information contained here was correct at the time of publication. Please check with the appropriate agency for any changes to the regulations or guidelines cited.