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Difference between revisions of "Hypermagnesemia"
From WikEM
Line 5: | Line 5: | ||
==Clinical Features== | ==Clinical Features== | ||
− | * | + | *Nausea and vomiting |
+ | *Loss of reflexes and diaphragmatic paralysis (at very high levels) | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Line 33: | Line 34: | ||
==Management== | ==Management== | ||
− | *[[IVF]] | + | *[[IVF]] |
− | *Furosemide 20-40mg | + | *Furosemide 20-40mg IV |
*CaCl 10% 5-10mL IV or Ca gluconate 10% 15-30mL IV over 5min | *CaCl 10% 5-10mL IV or Ca gluconate 10% 15-30mL IV over 5min | ||
− | *Consider HD for Mg > 8 or poor renal function | + | *Consider HD for Mg >8 or poor renal function |
==Disposition== | ==Disposition== |
Latest revision as of 01:38, 10 May 2017
Contents
Background
- High >3.5
- Magnesium is an effective calcium channel blocker both extracellularly and intracellularly[1]
- Intracellular magnesium profoundly blocks several cardiac potassium channels
Clinical Features
- Nausea and vomiting
- Loss of reflexes and diaphragmatic paralysis (at very high levels)
Differential Diagnosis
- Renal Failure
- Lithium
- Volume depletion
- Rhabdo
- IV Mg (goal in PET/eclampsia 5-7 mEq/L)
- Massive PO intake (laxative abusers, accidental Epsom salts)
- Magnesium enemas[2]
Evaluation
Mg Level | Signs/Symptoms |
---|---|
2-3 | Nausea |
3-4 | Somnolence |
4-8 | Loss of DTRs, muscle weakness |
8-12 | Respiratory depression |
12-15 | Hypotension, heart block, Cardiac Arrest, death |
Management
- IVF
- Furosemide 20-40mg IV
- CaCl 10% 5-10mL IV or Ca gluconate 10% 15-30mL IV over 5min
- Consider HD for Mg >8 or poor renal function