Sodium bicarbonate

Administration

• Type: 8.4% is common cardiac administered per
• Dosage Forms: 5% ; 7.5% ; 8.4% ; 4.2% ; 4% ; 325mg ; 150 mEq/1000 mL-D5% ; 150 mEq/1150 mL-D5%
• Routes of Administration: IV
• Common Trade Names: N/A
• Abbreviation: NaHOC3

Adult Dosing

Cardiac Arrest

50 mL (1 amp) IV push for severe acidemia and patient is adequately ventilated

• Frequency:
  • 1 mEq/kg IV bolus dose initially (~1-2 amps for average adult)
  • 0.5 mEq/kg/dose q10min
  • OR tailor to serial ABGs

IV drip

• 150 mEq/1000 mL inD5W

Pediatric Dosing

Cardiac Arrest

1 mL/kg IV push for severe acidemia and patient is adequately ventilated

Special Populations

• Pregnancy Rating: C
• Lactation risk: Infant risk minimal

Renal Dosing

• Adult:
• Pediatric:

Hepatic Dosing

• Adult:
• Pediatric:

Contraindications

• Allergy to class/drug
• Relative:
  • Ongoing chloride loss (vomiting, gastrointestinal suction, with concurrent diuretics that induce hypochloremia)

Adverse Reactions

Serious

• Extravasation- cellulitis, tissue necrosis, ulcer
• Metabolic alkalosis

Pharmacology

• Half-life:
• Metabolism:
• Excretion:

References

Authors

Daniel Ostermayer, Kevin Lu