What Are the Risk Factors?

There is no way to know for sure if you will get uterine cancer. Some women get it without being at high risk. However, several factors may increase the chance that you will get uterine cancer, including if you—

• Are older than 50.
• Are obese (have an abnormally high, unhealthy amount of body fat).
• Take estrogen by itself (without progesterone) for hormone replacement during menopause.
• Have had trouble getting pregnant, or have had fewer than five periods in a year before starting menopause.
• Take tamoxifen, a drug used to treat certain types of breast cancer.
• Have close family members who have had uterine, colon, or ovarian cancer.

If one or more of these things is true for you, it does not mean you will get uterine cancer. But you should speak with your doctor to see if he or she recommends more frequent exams.