Registry of Toxic Effects of Chemical Substances (RTECS)
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Bacillus subtilis carlsberg
RTECS #
CO9550000CAS #
9014-01-1Updated
September 201Molecular Weight
N/RMolecular Formula
N/RSynonyms
AlcalaseALK-enzyme
Bacillopeptidase A
Bacillopeptidase B
Bioprase
Colistinase
E.C. 3.4.21.14
E.C. 3.4.4.16
Maxatase
Nagarse
SP 266
Subtilisin (9CI)
Subtilisin (ACGIH)
Subtilisin bpn'
Subtilisin carlsburg
Subtilisin NOVO
Subtilisins
Subtilopeptidase A
Subtilopeptidase B
Subtilopeptidase bpn'
Subtilopeptidase C
Thermoase PC-10
Skin and Eye Irritation and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| eye /rabbit | 3 mg | moderate | FCTXAV 7,581,1969 |
Acute Toxicity Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| intratracheal/guinea pig | lowest published toxic dose: 20 µg/kg | Immunological Including Allergic: Increase in humoral response | TOXID9 60,175,2001 |
| oral/rat | lethal dose (50 percent kill): 3700 mg/kg | FCTXAV 7,581,1969 |
Other Multiple Dose Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| inhalation/mouse | lowest published toxic concentration: 0.1 pph/3D- intermittent | Lung, Thorax, or Respiration: Other changes Immunological Including Allergic: Increase in humoral response | TOXID9 60,10,2001 |
Reviews
| Organization | Standard | Reference |
|---|---|---|
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-ceiling concentration 0.00006 mg/m3 | DTLVS* TLV/BEI,2013 |
Standards and Regulations
| Organization | Standard | Reference |
|---|---|---|
| Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 0.0003 mg/m3 | DTLVS* 3,236,1971 |
| Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
| Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
| Occupational Exposure Limit-AUSTRALIA | time-weighted average 0.00006 mg/m3, JUL2008 | |
| Occupational Exposure Limit-DENMARK | ceiling concentration 0.00006 mg/m3, MAY2011 | |
| Occupational Exposure Limit-ICELAND | short term exposure limit 0.0006 mg/m3, sen, NOV2011 | |
| Occupational Exposure Limit-MEXICO | peak 0.00006 mg/m3, 2004 | |
| Occupational Exposure Limit-NEW ZEALAND | ceiling concentration 0.00006 mg/m3, sen, JAN2002 | |
| Occupational Exposure Limit-PERU | short term exposure limit 0,00006 mg/m3, JUL2005 | |
| Occupational Exposure Limit-SWEDEN | time-weighted average 1 glycine unit/m3, ceiling concentration 3 glycine unit/m3, Sen, JUN2005 | |
| Occupational Exposure Limit-SWITZERLAND | ceiling concentration 0.00006 mg/m3, sen, JAN2011 | |
| Occupational Exposure Limit-UNITED KINGDOM | time-weighted average 0.04 µg/m3, sen, OCT2007 |
NIOSH Documentation and Surveillance
| Organization | Standard | Reference |
|---|---|---|
| National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO SUBTILISINS-air | short term exposure limit 0.00006 mg/m3/60M | NIOSH* DHHS #92-100,1992 |
| National Occupational Exposure Survey 1983 | Hazard Code X1796; Number of Industries 3; Total Number of Facilities 225; Number of Occupations 5; Total Number of Employees Exposed 5548; Total Number of Female Employees Exposed 1814 |
Status in Federal Agencies
| Organization | Reference |
|---|---|
| EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
| EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8800 | |
| EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 |
- Page last reviewed:March 7, 2014
- Page last updated:February 6, 2017
- Content source:
- National Institute for Occupational Safety and Health (NIOSH) Education and Information Division