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Registry of Toxic Effects of Chemical Substances (RTECS)

Ethanamine

RTECS #

KH2100000

CAS #

75-04-7

Updated

September 201

Molecular Weight

45.10

Molecular Formula

C2H7N

Synonyms

1-Aminoethane
Aethylamine (German)
Aminoethane
Ethylamine
Ethylamine (ACGIH:OSHA)
Etilamina (Italian)
Etyloamina (Polish)
Monoethylamine

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 5 mg severeUCDS** 4/25/1958
eye /rabbit 50 ppm/10D- intermittent severeAMIHBC 3,287,1951
eye /rabbit 250 µg/24H severe85JCAE -,429,1986
skin /rabbit 500 mg/24H mild85JCAE -,429,1986

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mammal (species unspecified) lethal concentration (50 percent kill): 2300 mg/m3TPKVAL 14,80,1975
inhalation/rat lethal concentration (50 percent kill): 5540 ppm/1HENTOX* -,285,2005
inhalation/rat lethal concentration (50 percent kill): 5540 ppm/1HEye: Corneal damage

Lung, Thorax, or Respiration: Dyspnea		NTIS** OTS0538173
intravenous/rabbit lowest published lethal dose: 350 mg/kgHBAMAK 4,1295,1935
oral/rat lethal dose (50 percent kill): 400 mg/kgENTOX* -,285,2005
skin/rabbit lethal dose (50 percent kill): 270 mg/kgENTOX* -,285,2005
skin/rabbit lethal dose (50 percent kill): 390 µL/kgAMIHBC 10,61,1954

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 5 ppm;short term exposure limit 15 ppm (skin)DTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWCHREAY 9,389,1931
TOXICOLOGY REVIEWENTOX* -,285,2005

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 10 ppm (18 mg/m3)DTLVS* 3,103,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 2 ppm (3.8 mg/m3), short term exposure limit 6 ppm (11 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 5 ppm (9.4 mg/m3);KZW 10 ppm (18.8 mg/m3), 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 5 ppm (9.4 mg/m3), MAR2002
Occupational Exposure Limit-BELGIUMshort term exposure limit 15 ppm (28.2 mg/m3), Skin, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 5 ppm (9.2 mg/m3), skin, MAY2011
Occupational Exposure Limit-ECtime-weighted average 9.4 mg/m3 (5 ppm), JUN2000
Occupational Exposure Limit-FINLANDtime-weighted average 5 ppm (9.4 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 5 ppm (9.4 mg/m3), VLE 15 ppm (27 mg/m3), FEB2006
Occupational Exposure Limit-GERMANYMAK 5 ppm (9.4 mg/m3), 2011
Occupational Exposure Limit-HUNGARYtime-weighted average 9.4 mg/m3, short term exposure limit 9.4 mg/m3, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 5 ppm (9.2 mg/m3), skin, NOV2011
Occupational Exposure Limit-JAPANOccupational Exposure Limit 10 ppm (18 mg/m3), MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 10 ppm (18 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 10 ppm (18 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 10 ppm (18 mg/m3), skin, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 10 ppm (18 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 5 ppm (9 mg/m3); short term exposure limit 15 ppm (28 mg/m3), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 5 mg/m3, MAC(short term exposure limit) 15 mg/m3, JAN1999
Occupational Exposure Limit-RUSSIAshort term exposure limit 10 mg/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 10 ppm (18 mg/m3);short term exposure limit 15 ppm (30 mg/m3), Skin, JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 5 ppm (9 mg/m3), KZG-week 10 ppm (18 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 9 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 10 ppm (18 mg/m3), JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 10 ppm (18 mg/m3), JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 2 ppm (3.8 mg/m3);short term exposure limit 6 ppm (11 mg/m3), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 10 ppm (18 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 10 ppm (18 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 10 ppm (18 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 10 ppm (18 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ETHYLAMINE-air10H time-weighted average 10 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 31520; Number of Industries 2; Total Number of Facilities 31; Number of Occupations 2; Total Number of Employees Exposed 1797; Total Number of Female Employees Exposed 357
National Occupational Hazard Survey 1974Hazard Code 31520; Number of Industries 9; Total Number of Facilities 205; Number of Occupations 11; Total Number of Employees Exposed 4982

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
OSHA ANALYTICAL METHOD #36

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