Registry of Toxic Effects of Chemical Substances (RTECS)
Germane
RTECS #
LY4900000CAS #
7782-65-2Updated
September 201Molecular Weight
76.63Molecular Formula
GeH4Synonyms
Germanium hydrideGermanium tetrahydride
Germanium tetrahydride (ACGIH)
Monogermane
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/guinea pig | lethal concentration (50 percent kill): 260 mg/m3/4H | Brain and Coverings: Other degenerative changes | VCVN1* -,400,1988 |
inhalation/mouse | Lowest published lethal concentration: 2000 mg/m3/2H | Behavioral: Convulsions or effect on seizure threshold Nutritional and Gross Metabolic: Body temperature decrease | HBTME* -,557,2007 |
inhalation/mouse | lethal concentration (50 percent kill): 1380 mg/m3 | Behavioral: Excitement Behavioral: Ataxia Behavioral: Muscle contraction or spasticity | GTPZAB 18(2),56,1974 |
inhalation/rat | lethal concentration (50 percent kill): 1380 mg/m3 | Behavioral: Coma Brain and Coverings: Other degenerative changes | VCVN1* -,400,1988 |
inhalation/rat | Lowest published lethal concentration: 2000 mg/m3/4H | Behavioral: Convulsions or effect on seizure threshold Nutritional and Gross Metabolic: Body temperature decrease | HBTME* -,557,2007 |
oral/mouse | lethal dose (50 percent kill): 1250 mg/kg | Behavioral: Excitement Behavioral: Ataxia Behavioral: Muscle contraction or spasticity | GTPZAB 18(2),56,1974 |
Other Multiple Dose Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/rat | lowest published toxic concentration: 13 mg/m3/4H/30D- intermittent | Brain and Coverings: Changes in circulation Brain and Coverings: Other degenerative changes | VCVN1* -,400,1988 |
Reviews
Organization | Standard | Reference |
---|---|---|
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 0.2 ppm | DTLVS* TLV/BEI,2013 |
TOXICOLOGY REVIEW | HBTME* ,557,2007 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 0.2 ppm (0.6 mg/m3) | DTLWS* 3,20,1973 |
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
Occupational Exposure Limit-AUSTRALIA | time-weighted average 0.2 ppm (0.63 mg/m3), JUL2008 | |
Occupational Exposure Limit-AUSTRIA | MAK-TMW 0.2 ppm (0.6 mg/m3);KZW 0.4 ppm (1.2 mg/m3), 2007 | |
Occupational Exposure Limit-BELGIUM | time-weighted average 0.2 ppm (0.64 mg/m3), MAR2002 | |
Occupational Exposure Limit-DENMARK | time-weighted average 0.2 ppm (0.6 mg/m3), MAY2011 | |
Occupational Exposure Limit-FINLAND | short term exposure limit 0.2 ppm (0.64 mg/m3), NOV2011 | |
Occupational Exposure Limit-FRANCE | VME 0.2 ppm (0.6 mg/m3), FEB2006 | |
Occupational Exposure Limit-ICELAND | time-weighted average 0.2 ppm (0.6 mg/m3), NOV2011 | |
Occupational Exposure Limit-KOREA | time-weighted average 0.2 ppm (0.6 mg/m3), 2006 | |
Occupational Exposure Limit-MEXICO | time-weighted average 0.2 ppm (0.6 mg/m3);short term exposure limit 0.6 ppm (1.8 mg/m3), 2004 | |
Occupational Exposure Limit-NEW ZEALAND | time-weighted average 0.2 ppm (0.63 mg/m3), JAN2002 | |
Occupational Exposure Limit-NORWAY | time-weighted average 0.2 ppm (0.6 mg/m3), JAN1999 | |
Occupational Exposure Limit-PERU | time-weighted average 0,2 ppm (0,63 mg/m3), JUL2005 | |
Occupational Exposure Limit-RUSSIA | short term exposure limit 5 mg/m3, JUN2003 | |
Occupational Exposure Limit-SWITZERLAND | MAK-week 0.2 ppm (0.6 mg/m3), JAN2011 | |
Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 0.6 mg/m3, 2003 | |
Occupational Exposure Limit-UNITED KINGDOM | time-weighted average 0.2 ppm (0.64 mg/m3);short term exposure limit 0.6 ppm (1.9 mg/m3), OCT2007 |
NIOSH Documentation and Surveillance
Organization | Standard | Reference |
---|---|---|
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO GERMANIUM TETRAHYDRIDE-air | 10H time-weighted average 0.2 ppm | NIOSH* DHHS #92-100,1992 |
- Page last reviewed:March 7, 2014
- Page last updated:February 6, 2017
- Content source:
- National Institute for Occupational Safety and Health (NIOSH) Education and Information Division