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Registry of Toxic Effects of Chemical Substances (RTECS)

Indene

RTECS #

NK8225000

CAS #

95-13-6

Updated

September 201

Molecular Weight

116.17

Molecular Formula

C9H8

Synonyms

1H-Indene
Inden
Indene (ACGIH:OSHA)
Indonaphthene

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): 14 gm/m3GISAAA 41(4),104,1976
inhalation/rat lethal concentration (50 percent kill): 14000 mg/m3/4HVCVGH* -,218,1990
oral/mammal (species unspecified) lethal dose (50 percent kill): >5 gm/kgGISAAA 39(4),86,1974
unreported route/mouse lethal dose (50 percent kill): 1800 mg/kgVCVGH* -,218,1990
unreported route/rat lethal dose (50 percent kill): 2300 mg/kgVCVGH* -,218,1990

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 3 mg/m3/24H/15W- continuousKidney, Ureter, and Bladder: Other changes in urine composition

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Catalases		GISAAA 41(4),104,1976

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 5 ppmDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 10 ppm (45 mg/m3)DTLVS* 3,134,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 10 ppm (48 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 10 ppm (45 mg/m3);KZW 20 ppm (90 mg/m3), 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 10 ppm (49 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 10 ppm (45 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 10 ppm (48 mg/m3), short term exposure limit 20 ppm (96 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 10 ppm (45 mg/m3), FEB2006
Occupational Exposure Limit-ICELANDtime-weighted average 10 ppm (45 mg/m3), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 10 ppm (45 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 10 ppm (45 mg/m3);short term exposure limit 15 ppm (70 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 10 ppm (48 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 10 ppm (45 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 10 ppm (48 mg/m3), JUL2005
Occupational Exposure Limit-SWITZERLANDMAK-week 10 ppm (45 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 45 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 10 ppm (48 mg/m3);short term exposure limit 15 ppm (72 mg/m3), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 10 ppm (45 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 10 ppm (45 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO INDENE-air10H time-weighted average 10 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 39820; Number of Industries 1; Total Number of Facilities 31; Number of Occupations 1; Total Number of Employees Exposed 753; Total Number of Female Employees Exposed 376
National Occupational Hazard Survey 1974Hazard Code 39820; Number of Industries 24; Total Number of Facilities 3158; Number of Occupations 42; Total Number of Employees Exposed 61824

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

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