Registry of Toxic Effects of Chemical Substances (RTECS)
Isooctyl alcohol
RTECS #
NS7700000CAS #
26952-21-6Updated
September 201Molecular Weight
130.26Molecular Formula
C8H18OSynonyms
Exxal 8Isooctanol
Isooctyl alcohol (ACGIH)
Skin and Eye Irritation and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
eye /rabbit | 100 mg | severe | AIHAAP 34,493,1973 |
skin /rabbit | 2600 mg/24H | moderate | AIHAAP 34,493,1973 |
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
oral/mammal (species unspecified) | lethal dose (50 percent kill): 140 mg/kg | GISAAA 39(4),86,1974 | |
oral/mouse | lethal dose (50 percent kill): 1670 mg/kg | 85GMAT -,77,1982 | |
oral/rat | lethal dose (50 percent kill): 1480 mg/kg | Behavioral: Somnolence (general depressed activity) Lung, Thorax, or Respiration: Dyspnea | AIHAAP 34,493,1973 |
skin/rabbit | lethal dose (50 percent kill): 2520 mg/kg | 31ZTAS -,72,1968 | |
unreported route/mammal (species unspecified) | lethal dose (50 percent kill): 1670 mg/kg | GISAAA 51(5),61,1986 |
Other Multiple Dose Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/rat | lowest published toxic concentration: 1500 µg/m3/24H/96D- continuous | Blood: Other changes Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase | GISAAA 37(8),16,1972 |
inhalation/rat | lowest published toxic concentration: 600 mg/m3/6H/2W- intermittent | Kidney, Ureter, and Bladder: Changes in bladder weight Endocrine: Changes in spleen weight Blood: Changes in erythrocyte (RBC) count | NTIS** OTS0570889 |
Reviews
Organization | Standard | Reference |
---|---|---|
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 50 ppm (skin) | DTLVS* TLV/BEI,2013 |
Standards and Regulations
NIOSH Documentation and Surveillance
Organization | Standard | Reference |
---|---|---|
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ISOOCTYL ALCOHOL-air | 10H time-weighted average 50 ppm (Sk) | NIOSH* DHHS #92-100,1992 |
National Occupational Exposure Survey 1983 | Hazard Code 83573; Number of Industries 17; Total Number of Facilities 752; Number of Occupations 22; Total Number of Employees Exposed 12363; Total Number of Female Employees Exposed 3300 | |
National Occupational Hazard Survey 1974 | Hazard Code 83573; Number of Industries 6; Total Number of Facilities 160; Number of Occupations 19; Total Number of Employees Exposed 32085 |
Status in Federal Agencies
Organization | Reference |
---|---|
EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 |
- Page last reviewed:March 7, 2014
- Page last updated:February 6, 2017
- Content source:
- National Institute for Occupational Safety and Health (NIOSH) Education and Information Division