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Registry of Toxic Effects of Chemical Substances (RTECS)

Manganese oxide

RTECS #

OP0895000

CAS #

1317-35-7

Updated

September 201

Molecular Weight

228.82

Molecular Formula

Mn3O4

Synonyms

Manganese tetroxide (ACGIH)
Manganomanganic oxide
Trimanganese tetraoxide
Trimanganese tetroxide

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
oral/mouse 23 gm/kg (44D male)Reproductive: Paternal effects: Testes, epididymis, sperm duct

Reproductive: Paternal effects: Prostate, seminal vesicle, Cowper's gland, accessory glands		JTEHD6 6,861,1980

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse Lethal concentration: >3608 µg/m3/2HAIHAAP 41,494,1980
intratracheal/rat lowest published lethal dose: 375 mg/kgLung, Thorax, or Respiration: Emphysema

Lung, Thorax, or Respiration: Acute pulmonary edema		GISAAA 20(1),25,1955

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.02 mg(Mn)/m3 (resp)DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.1 mg(Mn)/m3 (inhal)DTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWMUREAV 727,72,2011
TOXICOLOGY REVIEWNBREV* 15,333,1991

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 1 mg(Mn)/m3 (dust), JUL2008
Occupational Exposure Limit-AUSTRALIAtime-weighted average 1 mg(Mn)/m3, short term exposure limit 3 mg(Mn)/m3 (fume), JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.2 mg(Mn)/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.2 mg(Mn)/m3 (dust), MAY2011
Occupational Exposure Limit-DENMARKtime-weighted average 0.2 mg(Mn)/m3 (fume), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 0.2 mg(Mn)/m3, inhal. dust, NOV2011
Occupational Exposure Limit-FINLANDtime-weighted average 0.1 mg(Mn)/m3, resp. dust, NOV2011
Occupational Exposure Limit-FRANCEVME 1 mg/m3, FEB2006
Occupational Exposure Limit-GERMANYMAK 0.02 mg(Mn)/m3 (resp), 0.2 mg(Mn)/m3 (inhal), 2011
Occupational Exposure Limit-HUNGARYtime-weighted average 5 mg(Mn)/m3, short term exposure limit 20 mg(Mn)/m3, SEP2000
Occupational Exposure Limit-JAPANOccupational Exposure Limit 0.2 mg(Mn)/m3, MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 5 mg(Mn)/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.2 mg(Mn)/m3;short term exposure limit 3 mg(Mn)/m3, 2004
Occupational Exposure Limit-MEXICOtime-weighted average 1 mg(Mn)/m3 (fume), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 1 mg(Mn)/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 2.5 mg(Mn)/m3, JAN1999
Occupational Exposure Limit-POLANDMAC(time-weighted average) 0.3 mg(Mn)/m3, MAC(C) 5 mg(Mn)/m3, JAN1999
Occupational Exposure Limit-SWEDENtime-weighted average 0.2 mg(Mn)/m3, (total dust);time-weighted average 0.1 mg(Mn)/m3, (resp. dust), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.5 mg(Mn)/m3, inhal, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 1 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.5 mg(Mn)/m3, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)ceiling concentration 5 mg(Mn)/m3CFRGBR 29,1915.1000,1993

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

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