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Registry of Toxic Effects of Chemical Substances (RTECS)

Pentaborane(9)

RTECS #

RY8925000

CAS #

19624-22-7

Updated

September 201

Molecular Weight

63.14

Molecular Formula

B5H9

Synonyms

Nonahydropentaborane
Pentaborane
Pentaborane (ACGIH:OSHA)

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/Dog lethal concentration (50 percent kill): 92 mg/m3/15MBehavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia		JPETAB 145,382,1964
inhalation/monkey lethal concentration (50 percent kill): 640 mg/m3/2MBehavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia		JPETAB 145,382,1964
inhalation/mouse lethal concentration (50 percent kill): 0.017 gm/m3/2HTPKVAL 9,7,1967
inhalation/mouse lethal concentration (50 percent kill): 6.8 ppm/2HTPKVAL 9,7,1967
inhalation/mouse lethal concentration (50 percent kill): 3400 ppb/4HAIHAAP 19,46,1958
inhalation/rat lethal concentration (50 percent kill): 18 mg/m3/4HVCVN1* -,199,1988
inhalation/rat lowest published toxic concentration: 18 mg/m3/30MBrain and Coverings: Other degenerative changesVCVN1* -,199,1988
inhalation/rat lethal concentration (50 percent kill): 6 ppm/4HAIHAAP 19,46,1958
intraperitoneal/Dog lowest published lethal dose: 15800 µg/kgPeripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Behavioral: Tremor

Behavioral: Coma		STGNBT -,191,1999
intraperitoneal/rat lethal dose (50 percent kill): 11100 µg/kg14KTAK -,693,1964

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/Dog lowest published toxic concentration: 3700 ppb/1H/3D- intermittentBehavioral: Convulsions or effect on seizure threshold

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field		TXAPA9 6,121,1964
inhalation/Dog lowest published toxic concentration: 2.6 mg/m3/4W- intermittentRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldVCVN1* -,199,1988
inhalation/hamster lowest published toxic concentration: 2.6 mg/m3/4W- intermittentRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldVCVN1* -,199,1988
inhalation/mouse lowest published toxic concentration: 3700 ppb/1H/4D- intermittentBehavioral: Convulsions or effect on seizure threshold

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field		TXAPA9 6,121,1964
inhalation/rabbit lowest published toxic concentration: 2.6 mg/m3/4W- intermittentRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldVCVN1* -,199,1988
inhalation/rat lowest published toxic concentration: 2.6 mg/m3/4W- intermittentRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldVCVN1* -,199,1988
inhalation/rat lowest published toxic concentration: 67 mg/m3/5M/5D- intermittentBehavioral: Tetany

Eye: Miosis (pupilliary constriction)

Eye: Conjunctiva irritation		VCVN1* -,199,1988
inhalation/rat lowest published toxic concentration: 30 mg/m3/5D- intermittentBehavioral: Tetany

Eye: Miosis (pupilliary constriction)

Eye: Conjunctiva irritation		VCVN1* -,199,1988
inhalation/rat lowest published toxic concentration: 7.8 mg/m3/60M/5D- intermittentBehavioral: Tetany

Eye: Miosis (pupilliary constriction)

Eye: Conjunctiva irritation		VCVN1* -,199,1988

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.005 ppm;short term exposure limit 0.015 ppmDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.005 ppm (0.01 mg/m3)DTLVS* 3,197,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.005 ppm (0.013 mg/m3), short term exposure limit 0.015 ppm (0.039 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 0.005 ppm (0.01 mg/m3);KZW 0.01 ppm (0.02 mg/m3), 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 0.005 ppm (0.013 mg/m3), MAR2002
Occupational Exposure Limit-BELGIUMshort term exposure limit 0.015 ppm (0.04 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.005 ppm (0.01 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 0.005 ppm (0.014 mg/m3), short term exposure limit 0.015 ppm (0.041 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 0.005 ppm (0.01 mg/m3), FEB2006
Occupational Exposure Limit-GERMANYMAK 0.005 ppm (0.013 mg/m3), 2011
Occupational Exposure Limit-ICELANDtime-weighted average 0.005 ppm (0.01 mg/m3), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 0.005 ppm (0.01 mg/m3), short term exposure limit 0.015 ppm (0.03 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.005 ppm (0.01 mg/m3);short term exposure limit 0.015 ppm, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.005 ppm (0.013 mg/m3), JAN2002
Occupational Exposure Limit-PERUtime-weighted average 0,005 ppm (0,013 mg/m3); short term exposure limit 0,015 ppm (0,039 mg/m3), JUL2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.005 ppm (0.01 mg/m3), KZG-week 0.01 ppm (0.02 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.01 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.005 ppm (0.01 mg/m3), JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 0.01 mg/m3, JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 0.005 ppm (0.01 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 0.005 ppm (0.01 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 0.005 ppm (0.01 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 0.005 ppm (0.01 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO PENTABORANE-air10H time-weighted average 0.005 ppm;short term exposure limit 0.015 ppmNIOSH* DHHS #92-100,1992

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
On EPA IRIS database

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