Registry of Toxic Effects of Chemical Substances (RTECS)
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Phenothiazine
RTECS #
SN5075000CAS #
92-84-2Updated
September 201Molecular Weight
199.28Molecular Formula
C12H9NSSynonyms
AFI-TiazinAgrazine
Antiverm
Biverm
Contaverm
Dibenzo-1,4-thiazine
Dibenzothiazine
ENT 38
Feeno
Fenothiazine (Dutch)
Fenotiazina (Italian)
Fenoverm
Fentiazin
Helmetina
Lethelmin
Nemazene
Orimon
Padophene
Penthazine
Phenegic
Phenosan
Phenothiazine (ACGIH)
Phenoverm
Phenovis
Phenoxur
Phenthiazine
Reconox
Souframine
Thiodifenylamine (Dutch)
Thiodiphenylamin (German)
Thiodiphenylamine
Tiodifenilamina (Italian)
Wurm-thional
XL-50
Reproductive Effects Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| oral/rat | 1250 mg/kg (1-22D pregnant) | Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants) | AJANA2 110,29,1962 |
Acute Toxicity Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| intravenous/mouse | lethal dose (50 percent kill): 178 mg/kg | CSLNX* NX#00586 | |
| oral/cattle | lethal dose (50 percent kill): 500 mg/kg | 85JCAE -,1104,1986 | |
| oral/child | lowest published lethal dose: 425 mg/kg/5D | Behavioral: Headache Liver: Jaundice, other or unclassified Blood: Normocytic anemia | LANCAO 242,86,1942 |
| oral/mouse | lethal dose (50 percent kill): 5 gm/kg | Behavioral: Antipsychotic | DNEUD5 7,45,1980 |
| oral/rabbit | lethal dose (50 percent kill): 4 gm/kg | 85JCAE -,1104,1986 | |
| unreported route/wild bird | lowest published lethal dose: 500 mg/kg | JACSAT 66,888,1944 |
Reviews
| Organization | Standard | Reference |
|---|---|---|
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 5 mg/m3 (skin) | DTLVS* TLV/BEI,2013 |
| TOXICOLOGY REVIEW | PLMJAP 6,160,1975 | |
| TOXICOLOGY REVIEW | CLCHAU 19,361,1973 | |
| TOXICOLOGY REVIEW | BLREV* 4,226,1990 | |
| TOXICOLOGY REVIEW | MEDIAV 37,263,2009 | |
| TOXICOLOGY REVIEW | NTAPM* -,689,1995 |
Standards and Regulations
| Organization | Standard | Reference |
|---|---|---|
| Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES | Cancelled | RBREV* -,198,1998 |
| Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 5 mg/m3 (skin) | DTLVS* 3,204,1971 |
| Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
| Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
| Occupational Exposure Limit-AUSTRALIA | time-weighted average 5 mg/m3, JUL2008 | |
| Occupational Exposure Limit-BELGIUM | time-weighted average 5 mg/m3, Skin, MAR2002 | |
| Occupational Exposure Limit-DENMARK | time-weighted average 5 mg/m3, skin, MAY2011 | |
| Occupational Exposure Limit-FINLAND | time-weighted average 5 mg/m3, short term exposure limit 10 mg/m3, skin, NOV2011 | |
| Occupational Exposure Limit-FRANCE | VME 5 mg/m3, Skin, FEB2006 | |
| Occupational Exposure Limit-ICELAND | time-weighted average 5 mg/m3, skin, NOV2011 | |
| Occupational Exposure Limit-KOREA | time-weighted average 5 mg/m3, skin, 2006 | |
| Occupational Exposure Limit-MEXICO | time-weighted average 5 mg/m3;short term exposure limit 10 mg/m3, 2004 | |
| Occupational Exposure Limit-NEW ZEALAND | time-weighted average 5 mg/m3, skin, JAN2002 | |
| Occupational Exposure Limit-NORWAY | time-weighted average 5 mg/m3, JAN1999 | |
| Occupational Exposure Limit-PERU | time-weighted average 5 mg/m3, JUL2005 | |
| Occupational Exposure Limit-SWITZERLAND | MAK-week 5 mg/m3, inhal, skin, JAN2011 | |
| Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 5 mg/m3, Skin, 2003 | |
| Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 5 mg/m3, Skin, JAN1993 |
NIOSH Documentation and Surveillance
| Organization | Standard | Reference |
|---|---|---|
| National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO PHENOTHIAZINE-air | 10H time-weighted average 5 mg/m3 (Sk) | NIOSH* DHHS #92-100,1992 |
| National Occupational Exposure Survey 1983 | Hazard Code 84116; Number of Industries 54; Total Number of Facilities 5473; Number of Occupations 68; Total Number of Employees Exposed 88048; Total Number of Female Employees Exposed 8791 | |
| National Occupational Hazard Survey 1974 | Hazard Code 84116; Number of Industries 5; Total Number of Facilities 175; Number of Occupations 15; Total Number of Employees Exposed 5639 |
Status in Federal Agencies
- Page last reviewed:March 7, 2014
- Page last updated:February 6, 2017
- Content source:
- National Institute for Occupational Safety and Health (NIOSH) Education and Information Division