Registry of Toxic Effects of Chemical Substances (RTECS)
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Phosphorus (white)
RTECS #
TH3500000CAS #
7723-14-0Updated
September 201Molecular Weight
123.88Molecular Formula
P4Synonyms
Bonide blue death rat killerCommon sense cockroach and rat preparations
Fosforo bianco (Italian)
Gelber phosphor (German)
Phosphore blanc (French)
Phosphorous (white)
Phosphorous yellow
Phosphorus (yellow)
Phosphorus, yellow (ACGIH:OSHA)
Rat-Nip
Tetrafosfor (Dutch)
Tetraphosphor (German)
Weiss phosphor (German)
White phosphorus
Yellow phosphorus
Reproductive Effects Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| oral/rat | 11 µg/kg (1-22D pregnant) | Reproductive: Effects on fertility: Female fertility index (e.g., # females pregnant per # sperm positive females; # females pregnant per # females mated) Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants) Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth) | ZDKAA8 36(5),87,1976 |
Acute Toxicity Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| oral/cat | lowest published lethal dose: 4 mg/kg | YKYUA6 28,329,1977 | |
| oral/Dog | lowest published lethal dose: 10 mg/kg | YKYUA6 28,329,1977 | |
| oral/duck | lowest published lethal dose: 3 mg/kg | Behavioral: Somnolence (general depressed activity) Behavioral: Convulsions or effect on seizure threshold Behavioral: Muscle weakness | JAPMA8 39,151,1950 |
| oral/duck | lethal dose (50 percent kill): 6.55 mg/kg | HBPTO* 2,1400,2001 | |
| oral/human | lowest published lethal dose: 0.7 mg/kg | HBPTO* 2,1402,2001 | |
| oral/human | lethal dose (90 percent kill): 26 mg/kg | HBPTO* 2,1402,2001 | |
| oral/infant | lowest published lethal dose: 0.4 mg/kg | HBPTO* 2,1402,2001 | |
| oral/mammal (species unspecified) | lowest published lethal dose: 200 mg/kg | 28ZEAL 4,321,1969 | |
| oral/mouse | lethal dose (50 percent kill): 4820 µg/kg | Behavioral: Somnolence (general depressed activity) Behavioral: Food intake (animal) Lung, Thorax, or Respiration: Other changes | NTIS** AD-B011-150 |
| oral/pig | lowest published lethal dose: 160 mg/kg | 28ZEAL 4,321,1969 | |
| oral/rat | lethal dose (50 percent kill): 3030 µg/kg | Behavioral: Somnolence (general depressed activity) Behavioral: Food intake (animal) Lung, Thorax, or Respiration: Other changes | NTIS** AD-B011-150 |
| oral/woman | lowest published lethal dose: 22 mg/kg | Cardiac: Cardiomyopathy including infarction | AHJOA2 84,139,1972 |
| oral/woman | lowest published toxic dose: 11 mg/kg | Gastrointestinal: Hypermotility, diarrhea Gastrointestinal: Nausea or vomiting Nutritional and Gross Metabolic: Body temperature increase | AJMSA9 209,223,1944 |
| oral/woman | lowest published lethal dose: 4600 µg/kg | Lung, Thorax, or Respiration: Cyanosis Gastrointestinal: Nausea or vomiting Skin and Appendages: Other: Sweating | AIMDAP 83,164,1949 |
| oral/woman | lowest published toxic dose: 2600 µg/kg | Behavioral: Fluid intake Gastrointestinal: Hypermotility, diarrhea Gastrointestinal: Nausea or vomiting | NEJMAG 232,247,1945 |
| subcutaneous/Dog | lowest published lethal dose: 2 mg/kg | Behavioral: Food intake (animal) Cardiac: Other changes Liver: Fatty liver degeneration | AEXPBL 52,173,1905 |
| subcutaneous/rabbit | lowest published lethal dose: 10 mg/kg | Behavioral: Muscle weakness Endocrine: Hypoglycemia | AEXPBL 64,274,1911 |
Other Multiple Dose Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| inhalation/rabbit | lowest published toxic concentration: 160 mg/m3/30M/60D- intermittent | Blood: Pigmented or nucleated red blood cells Blood: Changes in erythrocyte (RBC) count Blood: Changes in leukocyte (WBC) count | FKIZA4 46,604,1955 |
| oral/duck | lowest published toxic dose: 14 mg/kg/14D- intermittent | Behavioral: Somnolence (general depressed activity) Liver: Fatty liver degeneration Kidney, Ureter, and Bladder: Other changes | JAPMA8 39,151,1950 |
| oral/guinea pig | lowest published toxic dose: 105 mg/kg/35W- intermittent | Liver: Hepatitis, fibrous (cirrhosis, post- necrotic scarring) Liver: Change in gall bladder structure or function Liver: Other changes | PSEBAA 67,351,1945 |
| oral/rat | lowest published toxic dose: 18 mg/kg/4W- intermittent | Liver: Other changes Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymes | WDZAEK 4,206,1990 |
| oral/rat | lowest published toxic dose: 12 mg/kg/4D- intermittent | Liver: Hepatitis (hepatocellular necrosis), diffuse Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases | WDZAEK 4,4,1990 |
| oral/rat | lowest published toxic dose: 20800 µg/kg/16D- continuous | Musculoskeletal: Other changes | ANREAK 177,15,1973 |
| oral/rat | lowest published toxic dose: 85 mg/m3/17W- intermittent | Liver: Fatty liver degeneration Liver: Hepatitis, fibrous (cirrhosis, post- necrotic scarring) Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation) | GTPZAB 26(9),17,1982 |
| oral/rat | lowest published toxic dose: 91 µg/kg/26W- intermittent | Behavioral: Alteration of classical conditioning Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase | GISAAA 44(5),74,1979 |
| oral/rat | lowest published toxic dose: 11088 µg/kg/22W- continuous | Nutritional and Gross Metabolic: Weight loss or decreased weight gain | JPETAB 24,119,1925 |
Reviews
| Organization | Standard | Reference |
|---|---|---|
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 0.1 mg/m3 | DTLVS* TLV/BEI,2013 |
| TOXICOLOGY REVIEW | NTIS** AD778-725 | |
| TOXICOLOGY REVIEW | DIMON* 39,678,1993 | |
| TOXICOLOGY REVIEW | HUTOX* -,683,1996 | |
| TOXICOLOGY REVIEW | HTOPA* 1,595,2002 | |
| TOXICOLOGY REVIEW | CCACL* 21,719,2005 | |
| TOXICOLOGY REVIEW | OSMPR* 102,433,2006 |
Standards and Regulations
| Organization | Standard | Reference |
|---|---|---|
| Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION | FEREAC 54,7740,1989 | |
| Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 0.1 mg/m3 | DTLVS* 3,210,1971 |
| Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
| Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
| Occupational Exposure Limit-ARAB Republic of Egypt | time-weighted average 0.1 mg/m3, JAN1993 | |
| Occupational Exposure Limit-AUSTRALIA | time-weighted average 0.1 mg/m3, JUL2008 | |
| Occupational Exposure Limit-AUSTRIA | MAK-TMW 0.1 mg/m3;KZW 0.2 mg/m3, inhal, 2007 | |
| Occupational Exposure Limit-BELGIUM | time-weighted average 0.02 ppm (0.1 mg/m3), MAR2002 | |
| Occupational Exposure Limit-DENMARK | time-weighted average 0.1 mg/m3, MAY2011 | |
| Occupational Exposure Limit-FINLAND | short term exposure limit 0.1 mg/m3, NOV2011 | |
| Occupational Exposure Limit-FRANCE | VME 0.1 mg/m3, VLE 0.3 mg/m3, FEB2006 | |
| Occupational Exposure Limit-GERMANY | MAK 0.01 mg/m3, inhal, 2011 | |
| Occupational Exposure Limit-HUNGARY | time-weighted average 0.1 mg/m3, short term exposure limit 0.1 mg/m3, SEP2000 | |
| Occupational Exposure Limit-ICELAND | time-weighted average 0.1 mg/m3, NOV2011 | |
| Occupational Exposure Limit-JAPAN | Occupational Exposure Limit 0.1 mg/m3, MAY2012 | |
| Occupational Exposure Limit-KOREA | time-weighted average 0.1 mg/m3, 2006 | |
| Occupational Exposure Limit-MEXICO | time-weighted average 0.1 mg/m3;short term exposure limit 0.3 mg/m3, 2004 | |
| Occupational Exposure Limit-NEW ZEALAND | time-weighted average 0.1 mg/m3, JAN2002 | |
| Occupational Exposure Limit-POLAND | MAC(time-weighted average) 0.3 mg/m3, JAN1993 | |
| Occupational Exposure Limit-RUSSIA | time-weighted average 0.03 mg/m3, short term exposure limit 0.1 mg/m3, JUN2003 | |
| Occupational Exposure Limit-SWITZERLAND | MAK-week 0.05 mg/m3, KZG-week 0.1 mg/m3, inhal, JAN2011 | |
| Occupational Exposure Limit-THAILAND | time-weighted average 0.1 mg/m3, JAN1993 | |
| Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 0.1 mg/m3, 2003 | |
| Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 0.1 mg/m3, JAN1993 | |
| Occupational Exposure Limit-TURKEY | time-weighted average 0.1 mg/m3, JAN1993 | |
| Occupational Exposure Limit-UNITED KINGDOM | time-weighted average 0.1 mg/m3;short term exposure limit 0.3 mg/m3, OCT2007 | |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 0.1 mg/m3 | CFRGBR 29,1926.55,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 0.1 mg/m3 | CFRGBR 41,50-204.50,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 0.1 mg/m3 | CFRGBR 29,1910.1000,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 0.1 mg/m3 | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
| Organization | Standard | Reference |
|---|---|---|
| National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO PHOSPHORUS (YELLOW)-air | 10H time-weighted average 0.1 mg/m3 | NIOSH* DHHS #92-100,1992 |
| National Occupational Exposure Survey 1983 | Hazard Code M0004; Number of Industries 1; Total Number of Facilities 75; Number of Occupations 1; Total Number of Employees Exposed 675; Total Number of Female Employees Exposed 225 | |
| National Occupational Exposure Survey 1983 | Hazard Code M0005; Number of Industries 1; Total Number of Facilities 6; Number of Occupations 1; Total Number of Employees Exposed 91; Total Number of Female Employees Exposed 6 | |
| National Occupational Exposure Survey 1983 | Hazard Code 81650; Number of Industries 104; Total Number of Facilities 12775; Number of Occupations 88; Total Number of Employees Exposed 208975; Total Number of Female Employees Exposed 7598 | |
| National Occupational Exposure Survey 1983 | Hazard Code 81684; Number of Industries 5; Total Number of Facilities 139; Number of Occupations 10; Total Number of Employees Exposed 2924; Total Number of Female Employees Exposed 67 | |
| National Occupational Hazard Survey 1974 | Hazard Code M0004; Number of Industries 2; Total Number of Facilities 38; Number of Occupations 3; Total Number of Employees Exposed 205 | |
| National Occupational Hazard Survey 1974 | Hazard Code M0005; Number of Industries 1; Total Number of Facilities 41; Number of Occupations 5; Total Number of Employees Exposed 626 | |
| National Occupational Hazard Survey 1974 | Hazard Code 81650; Number of Industries 19; Total Number of Facilities 1187; Number of Occupations 42; Total Number of Employees Exposed 13630 | |
| National Occupational Hazard Survey 1974 | Hazard Code 81684; Number of Industries 3; Total Number of Facilities 47; Number of Occupations 4; Total Number of Employees Exposed 261 |
Status in Federal Agencies
- Page last reviewed:March 7, 2014
- Page last updated:February 6, 2017
- Content source:
- National Institute for Occupational Safety and Health (NIOSH) Education and Information Division