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Registry of Toxic Effects of Chemical Substances (RTECS)

1-Propanethiol

RTECS #

TZ7300000

CAS #

107-03-9

Updated

October 1997

Molecular Weight

76.17

Molecular Formula

C3H8S

Synonyms

1-Mercaptopropane
n-Propyl mercaptan
n-Propylthiol
Propane-1-thiol
Propyl mercaptan
Propylthiol

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 83 mg severeAIHAAP 19,171,1958

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lethal concentration (50 percent kill): 4010 ppm/4HLung, Thorax, or Respiration: Respiratory stimulation

Behavioral: Somnolence (general depressed activity)

Eye: Chromodacryorrhea		AIHAAP 19,171,1958
inhalation/rat lethal concentration (50 percent kill): 7300 ppm/4HLung, Thorax, or Respiration: Respiratory stimulation

Behavioral: Somnolence (general depressed activity)

Eye: Lacrimation		AIHAAP 19,171,1958
intraperitoneal/rat lethal dose (50 percent kill): 515 mg/kgBehavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Respiratory depression

Behavioral: Coma		AIHAAP 19,171,1958
oral/rat lethal dose (50 percent kill): 1790 mg/kgBehavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Respiratory depression

Behavioral: Coma		AIHAAP 19,171,1958

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

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