Registry of Toxic Effects of Chemical Substances (RTECS)
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n-Propyl nitrate
RTECS #
UK0350000CAS #
627-13-4Updated
September 201Molecular Weight
105.11Molecular Formula
C3H7NO3Synonyms
Nitrate de propyle normal (French)Nitric acid, propyl ester
n-Propyl nitrate (ACGIH:OSHA)
Propyl nitrate
Propylester kyseliny dusicne (Czech)
Acute Toxicity Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| inhalation/mouse | Lowest published lethal concentration: 5816 ppm/4H | Behavioral: Convulsions or effect on seizure threshold Lung, Thorax, or Respiration: Cyanosis | AIHAAP 19,80,1958 |
| inhalation/rat | Lowest published lethal concentration: 5816 ppm/4H | Behavioral: Somnolence (general depressed activity) Lung, Thorax, or Respiration: Cyanosis | AIHAAP 19,80,1958 |
| intravenous/cat | lowest published lethal dose: 100 mg/kg | JPETAB 118,77,1956 | |
| intravenous/Dog | lowest published lethal dose: 200 mg/kg | JPETAB 118,77,1956 | |
| intravenous/rabbit | lethal dose (50 percent kill): 200 mg/kg | JPETAB 118,77,1956 |
Reviews
| Organization | Standard | Reference |
|---|---|---|
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 25 ppm;short term exposure limit 40 ppm | DTLVS* TLV/BEI,2013 |
Standards and Regulations
| Organization | Standard | Reference |
|---|---|---|
| Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 25 ppm (110 mg/m3) | DTLVS* 3,217,1971 |
| Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
| Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
| Occupational Exposure Limit-AUSTRALIA | time-weighted average 25 ppm (107 mg/m3), short term exposure limit 40 ppm (172 mg/m3), JUL2008 | |
| Occupational Exposure Limit-AUSTRIA | MAK-TMW 25 ppm (110 mg/m3), 2007 | |
| Occupational Exposure Limit-BELGIUM | time-weighted average 25 ppm (109 mg/m3), short term exposure limit 40 ppm (174 mg/m3), MAR2002 | |
| Occupational Exposure Limit-DENMARK | time-weighted average 25 ppm (110 mg/m3), MAY2011 | |
| Occupational Exposure Limit-FINLAND | time-weighted average 25 ppm (110 mg/m3), short term exposure limit 40 ppm (170 mg/m3), NOV2011 | |
| Occupational Exposure Limit-FRANCE | VME 25 ppm (105 mg/m3), FEB2006 | |
| Occupational Exposure Limit-ICELAND | time-weighted average 25 ppm (110 mg/m3), NOV2011 | |
| Occupational Exposure Limit-KOREA | time-weighted average 25 ppm (105 mg/m3), short term exposure limit 40 ppm (170 mg/m3), 2006 | |
| Occupational Exposure Limit-MEXICO | time-weighted average 25 ppm (105 mg/m3);short term exposure limit 40 ppm (170 mg/m3), 2004 | |
| Occupational Exposure Limit-NEW ZEALAND | time-weighted average 25 ppm (107 mg/m3), short term exposure limit 40 ppm (172 mg/m3), JAN2002 | |
| Occupational Exposure Limit-NORWAY | time-weighted average 20 ppm (90 mg/m3), JAN1999 | |
| Occupational Exposure Limit-PERU | time-weighted average 25 ppm (107 mg/m3); short term exposure limit 40 ppm (172 mg/m3), JUL2005 | |
| Occupational Exposure Limit-SWITZERLAND | MAK-week 25 ppm (110 mg/m3), KZG-week 50 ppm (220 mg/m3), JAN2011 | |
| Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 1 10 mg/m3, 2003 | |
| Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 25 ppm (110 mg/m3), JAN1993 | |
| Occupational Exposure Limit-TURKEY | time-weighted average 25 ppm (110 mg/m3), JAN1993 | |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 25 ppm (110 mg/m3) | CFRGBR 29,1926.55,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 25 ppm (110 mg/m3) | CFRGBR 41,50-204.50,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 25 ppm (110 mg/m3) | CFRGBR 29,1910.1000,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 25 ppm (110 mg/m3) | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
| Organization | Standard | Reference |
|---|---|---|
| National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO n-PROPYL NITRATE-air | 10H time-weighted average 25 ppm;short term exposure limit 40 ppm | NIOSH* DHHS #92-100,1992 |
| National Occupational Exposure Survey 1983 | Hazard Code X7139; Number of Industries 2; Total Number of Facilities 30; Number of Occupations 2; Total Number of Employees Exposed 1844; Total Number of Female Employees Exposed 272 |
- Page last reviewed:March 7, 2014
- Page last updated:February 6, 2017
- Content source:
- National Institute for Occupational Safety and Health (NIOSH) Education and Information Division