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Registry of Toxic Effects of Chemical Substances (RTECS)

Pyrophosphoric acid, tetrasodium salt

RTECS #

UX7350000

CAS #

7722-88-5

Updated

July 2013

Molecular Weight

265.90

Molecular Formula

O7P2·4Na

Synonyms

Anhydrous tetrasodium pyrophosphate
Natrium pyrophosphat (German)
Phosphotex
Pyrophosphate
Tetranatriumpyrophosphat (German)
Tetrasodium diphosphate
Tetrasodium pyrophosphate
Tetrasodium pyrophosphate (ACGIH)
Tetrasodium pyrophosphate, anhydrous
TSPP
Victor TSPP

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat lethal dose (50 percent kill): 59 mg/kgBehavioral: Excitement

Nutritional and Gross Metabolic: Weight loss or decreased weight gain		JPETAB 108,117,1953
intravenous/mouse lethal dose (50 percent kill): 69 mg/kgARZNAD 7,445,1957
intravenous/rat lethal dose (50 percent kill): 100 mg/kgARZNAD 7,172,1957
oral/mouse lethal dose (50 percent kill): 2980 mg/kgARZNAD 7,445,1957
oral/rat lethal dose (50 percent kill): 4 gm/kgARZNAD 7,172,1957
skin/rabbit Lethal dose: >300 mg/kgATDAEI 1,47,1990
subcutaneous/mouse lethal dose (50 percent kill): 400 mg/kgARZNAD 7,445,1957

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWARZNAD 7,24,1957

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESCancelledRBREV* -,319,1998
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 5 mg/m3, JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 5 mg/m3;KZW 10 mg/m3, inhal, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 5 mg/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 5 mg/m3, MAY2011
Occupational Exposure Limit-FRANCEVME 5 mg/m3, FEB2006
Occupational Exposure Limit-ICELANDtime-weighted average 5 mg/m3, NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 5 mg/m3, 2006
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 5 mg/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 5 mg/m3, JAN1999
Occupational Exposure Limit-PERUtime-weighted average 5 mg/m3, JUL2005
Occupational Exposure Limit-SWITZERLANDMAK-week 5 mg/m3, inhal, JAN2011
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 5 mg/m3, OCT2007

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO TETRASODIUM PYROPHOSPHATE-air10H time-weighted average 5 mg/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 80224; Number of Industries 223; Total Number of Facilities 31059; Number of Occupations 144; Total Number of Employees Exposed 566370; Total Number of Female Employees Exposed 244801
National Occupational Hazard Survey 1974Hazard Code 80224; Number of Industries 179; Total Number of Facilities 22297; Number of Occupations 108; Total Number of Employees Exposed 177064

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

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