Methamphetamines - Method 9106

Proposed NIOSH 9106 for Methamphetamine and Illicit Drugs, Precursors, and Adulterants by Liquid-Liquid Extraction and Gas Chromatography-Mass Spectrometry (GC/MS) is a sampling and analytical method that will be included in the NIOSH Manual of Analytical Methods, 5th edition. Two other proposed methamphetamine wipe methods will also be included. NIOSH 9109 is a Solid Phase Extraction Gas Chromatography-Mass Spectrometry (GC/MS) method and NIOSH 9111 is a Liquid Chromatography-Mass Spectrometry (LC/MS) method. NIOSH Method 9106 produces cleaner chromatograms and has longer operating times between mass spectrometer cleanings than NIOSH 9109 or NIOSH 9111. NIOSH 9109 has a quicker sample preparation time to run a larger number of samples, but has more problems with interferences than NIOSH 9106. NIOSH 9111 is the quickest and least expensive of the three methods, but has only been evaluated for the measurement of methamphetamine and not other illicit drugs of interest.

Material Under Consideration

NIOSH Final document: Methamphetamine and Illicit Drugs, Precursors and Adulterants on Wipes by Liquid-Liquid Extraction – NIOSH Method 9106; 10/17/11 [PDF - 24,597 KB]

Draft NIOSH document; (Methamphetamine and Illicit Drugs, Precursors, and Adulterants on Wipes by Liquid-Liquid Extraction) – 8/30/05 [PDF - 46,530 KB]

Draft NIOSH document; (NIOSH Manual of Analytical Methods (NMAM) Fifth Edition; Methamphetamine and Illicit Drugs, Precursors, and Adulterants on Wipes by Liquid-Liquid Extraction) – 1/1/09 [PDF - 25,751 KB]

Submissions in order of Receipt

NIOSH responses to external review comments – 6/1/11 [PDF - 11,579 KB]

Submission to the docket from Groff (Research Chemist) – 3/31/08 [PDF - 1,473 KB]

Submission to the docket from external reviewer (1) – 10/1/09 [PDF - 1,863 KB]

Reference (1); Martyny JW (2008). Variability in the Analysis of Wipe Samples Taken for Methamphetamine Contamination; 3/19/08 [PDF - 24,423 KB]

Reference (2); Martyny JW (2008). Methamphetamine Sampling Variability on Different Surfaces using Different Solvents; 10/1/08 [PDF - 15,205 KB]

Reference (3); Martyny JW (2008). Decontamination of Building Materials Contaminated with Methamphetamine; 1/1/08 [PDF - 14,029 KB]

Submission to the docket from external reviewer (2) – 10/1/09 [PDF - 1,086 KB]

Submission to the docket from external reviewer (3) – 10/1/09 [PDF - 955 KB]

Submission to the docket from external reviewer (4) – 10/1/09 [PDF - 4,236 KB]

Submission to the docket from external reviewer (5) – 10/1/09 [PDF - 1,756 KB]