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NIOSH

DIACETONE ALCOHOL

ICSC: 0647

4-Hydroxy-4-methylpentan-2-one
2-Pentanone, 4-hydroxy-4-methyl-
4-Hydroxy-2-keto-4-methylpentane
4-Hydroxy-4-methyl-2-pentanone
C6H12O2 / (CH3)2C(OH)CH2COCH3
Molecular mass: 116.2
ICSC # 0647 		CAS # 123-42-2
RTECS # SA9100000
UN # 1148
EC # 603-016-00-1
April 19, 2005 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Flammable. See Notes.
NO open flames, NO sparks, and NO smoking.
Water spray. Alcohol-resistant foam. Dry powder. Carbon dioxide.
EXPLOSION Above 58°C explosive vapour/air mixtures may be formed. (See Notes.)
Above 58°C use a closed system, ventilation, and explosion-proof electrical equipment. Use non-sparking handtools.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE


•INHALATION Cough. Sore throat.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest.
•SKIN Redness. Dry skin. MAY BE ABSORBED!
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
•EYES Redness. Pain.
Safety goggles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Remove all ignition sources. Personal protection: filter respirator for organic gases and vapours. Cover the spilled material with absorbent. Carefully collect remainder.
Fireproof. Separated from acids, bases , amines and oxidants .

Xi symbol
R: 36
S: 2-24/25
UN Hazard Class: 3
UN Packing Group: III
ICSC: 0647 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

DIACETONE ALCOHOL

ICSC: 0647

I

M

P

O

R

T

A

N

T


D

A

T

A

PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on heating or on burning or on contact with acids , bases and amines producing acetone and mesityl alcohol. Reacts violently with oxidants forming flammable/explosive gas (hydrogen - see ICSC0001)

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 50 ppm as TWA; (ACGIH 2005).
MAK: 20 ppm, 96 mg/m3;
Peak limitation category: I(2);
skin absorption (H);
Pregnancy risk group: D;
(DFG 2006).
OSHA PEL: TWA 50 ppm (240 mg/m3)
NIOSH REL: TWA 50 ppm (240 mg/m3)
NIOSH IDLH: 1800 ppm 10%LEL See: 123422


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes , the skin and the respiratory tract . If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis. Exposure far above the OEL may result in lowering of consciousness.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The liquid defats the skin.

PHYSICAL
PROPERTIES

Boiling point: 169-171°C
Melting point: -47°C
Relative density (water = 1): 0.93
Solubility in water:
miscible
Vapour pressure, kPa at 20°C: 0.108
Relative vapour density (air = 1): 4.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.0048
Flash point:
58°C c.c.
Auto-ignition temperature: 640°C
Explosive limits, vol% in air: 1.8-6.9
Octanol/water partition coefficient as log Pow: -0.14 to 1.03 (calculated)

ENVIRONMENTAL
DATA


N O T E S

This card is only valid for the pure substance.The technical product may contain up to 5% acetone (see ICSC 0087), resulting in high flammability. Other UN Classification for technical product: UN hazard class 3, UN pack group II.
Transport Emergency Card: TEC (R)-30GF1-III

NFPA Code: H1; F2; R0;
Card has been partially updated in August 2007: see Ingestion First Aid, Occupational Exposure Limits.

ADDITIONAL INFORMATION



ICSC: 0647 DIACETONE ALCOHOL
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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