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NIOSH

p-NITROCHLOROBENZENE

ICSC: 0846

1-Chloro-4-nitrobenzene
PCNB
PNCB
NO2C6H4Cl
Molecular mass: 157.6
ICSC # 0846 		CAS # 100-00-5
RTECS # CZ1050000
UN # 1578
EC # 610-005-00-5
August 10, 1997 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible. Many reactions may cause fire or explosion.
NO open flames.
Powder, water spray, foam, carbon dioxide.
EXPLOSION

Combat fire from a sheltered position.
EXPOSURE
STRICT HYGIENE!

•INHALATION Blue lips or finger nails. Dizziness. Headache. Nausea. Vomiting. Weakness.
Local exhaust or breathing protection.
Fresh air, rest. Refer for medical attention.
•SKIN MAY BE ABSORBED! (See Inhalation).
Protective gloves. Protective clothing.
First rinse with plenty of water, then remove contaminated clothes and rinse again. Rinse skin with plenty of water or shower. Refer for medical attention.
•EYES
Safety goggles, face shield, or eye protection in combination with breathing protection if powder.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION (See Inhalation).

Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!).

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT absorb in saw-dust or other combustible absorbents. Do NOT let this chemical enter the environment. (Extra personal protection: complete protective clothing including self-contained breathing apparatus).
Separated from combustible and reducing substances, food and feedstuffs. Keep in a well-ventilated room.
Do not transport with food and feedstuffs.
T symbol
N symbol
R: 23/24/25-40-48/20/21/22-68-51/53
S: 1/2-28-36/37-45-61
UN Hazard Class: 6.1
UN Packing Group: II
ICSC: 0846 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

p-NITROCHLOROBENZENE

ICSC: 0846

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PHYSICAL STATE; APPEARANCE:
YELLOWISH CRYSTALS , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on heating producing toxic gases (nitrogen oxides, hydrogen chloride, phosgene and chlorine). The substance is a strong oxidant and reacts violently with combustible and reducing materials.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.1 ppm as TWA; (skin) A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2008).
MAK: skin absorption (H);
Carcinogen category: 3B
(DFG 2008).
OSHA PEL: TWA 1 mg/m3 skin
NIOSH REL: Ca See Appendix A skin
NIOSH IDLH: Ca 100 mg/m3 See: 100005


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the blood , resulting in formation of methaemoglobin. See Notes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact may cause skin sensitization.

PHYSICAL
PROPERTIES

Boiling point: 242°C
Melting point: 82-84°C
Relative density (water = 1): 1.3
Solubility in water: none
Vapour pressure, Pa at 30°C: 20
Relative vapour density (air = 1): 5.44
Flash point: 127°C c.c.
Octanol/water partition coefficient as log Pow: 2.39

ENVIRONMENTAL
DATA

The substance is toxic to aquatic organisms. The substance may cause long-term effects in the aquatic environment.

N O T E S

Depending on the degree of exposure, periodic medical examination is indicated.
Transport Emergency Card: TEC (R)-877

NFPA Code: H3; F1; R2;
Card has been partially updated in November 2008: see Occupational Exposure Limits,

ADDITIONAL INFORMATION



ICSC: 0846 p-NITROCHLOROBENZENE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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