2013 Interpretive Criteria for Neisseria gonorrhoeae Susceptibility Testing
The following are zone diameter interpretive standards and equivalent minimal inhibitory concentration (MIC) breakpoints* for Neisseria gonorrhoeae according to the Clinical and Laboratory Standards Institute (Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Third Informational Supplement, January 2013, M100-S23 Vol 33 No 1::
*At this time, no interpretive criteria exists for Azithromycin and Levofloxacin
Antimicrobial Agent | Zone Diameter (nearest whole mm) | Equivalent MIC Breakpoints (µg/mL) | |||
---|---|---|---|---|---|
R | I | S | R | S | |
Penicillins | |||||
Penicillin | <=26 | 27-46 | >=47 | >=2 | <=0.06 |
Cephems (Parenteral) | |||||
Cefotaxime | - | - | >=31 | - | <=0.5 |
Ceftizoxime | - | - | >=38 | - | <=0.5 |
Ceftriaxone | - | - | >=35 | - | <=0.25 |
Cefmetazole | <=27 | 28-32 | >=33 | >=8 | <=2 |
Cefotetan | <=19 | 20-25 | >=26 | >=8 | <=2 |
Cefoxitin | <=23 | 24-27 | >=28 | >=8 | <=2 |
Cefuroxime sodium (parenteral) | <=25 | 26-30 | >=31 | >=4 | <=1 |
Cefepime | - | - | >=31 | - | <=0.5 |
Ceftazidime | - | - | >=31 | - | <=0.5 |
Cephems (Oral) | |||||
Cefixime | - | - | >=31 | - | <=0.25 |
Cefpodoxime | - | - | >=29 | - | <=0.5 |
Cefetamet | - | - | >=29 | - | <=0.5 |
Tetracyclines | |||||
Tetracycline | <=30 | 31-37 | >=38 | >=2 | <=0.25 |
Fluoroquinolones | |||||
Ciprofloxacin | <=27 | 28-40 | >=41 | >=1 | <=0.06 |
Gatifloxacin | <=33 | 34-37 | >=38 | >=0.5 | <=0.12 |
Ofloxacin | <=24 | 25-30 | >=31 | >=2 | <=0.25 |
Enoxacin | <=31 | 32-35 | >=36 | >=2 | <=0.5 |
Grepafloxacin | <=27 | 28-36 | >=37 | >=1 | <=0.06 |
Lomefloxacin | <=26 | 27-37 | >=38 | >=2 | <=0.12 |
Trovafloxacin | - | - | >=34 | - | <=0.25 |
Fleroxacin | <=28 | 29-34 | >=35 | >=1 | <=0.25 |
Aminocyclitols | |||||
Spectinomycin | <=14 | 15-17 | >=18 | >=128 | <=32 |
- Page last reviewed: November 18, 2013
- Page last updated: November 18, 2013
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