Anticoagulants

Vitamin K Antagonist

Blocks activation of vitamin K dependent prothrombotic factors II, VII, IX, X and blocks synthesis of vitamin K dependent ANTI-thrombotic proteins C and S

• Warfarin

Heparins

Bind to and activate antithrombin, which in turns inactivates factor Xa and thrombin

• Unfractionated heparin
• Low molecular weight heparin
  • Enoxaparin (Lovenox)
  • Dalteparin

Factor Xa Inhibitors

Inhibits Factor Xa, leading to inactivation of thrombin

• Rivaroxaban (Xarelto)
• Apixaban (Eliquis)
• Fondaparinux
• Edoxaban

Direct Thrombin Inhibitors

Self-explanatory

• Dabigatran
• Argatroban
• Bivalirudin

See Also

• Anticoagulant reversal for life-threatening bleeds
• Antiplatelet medications

Authors

Claire