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Cefprozil
From WikEM
Contents
Administration
- Type: antibiotic
- Dosage Forms: PO
- Routes of Administration: PO
- Common Trade Names: Cefzil
Adult Dosing
Infections, bacterial:
- 250-500mg PO q12h x 10 days
Pediatric Dosing
infections, bacterial:
- 30mg/kg/day PO divided q12h x 10 days, max 1000mg/day
Special Populations
- Pregnancy Rating: B
- Lactation risk: probably safe
Renal Dosing
- Adult: CrCl < 30: decrease dose 50%
- Pediatric:CrCl < 30: decrease dose 50%
Hepatic Dosing
- Adult: none defined
- Pediatric: none defined
Contraindications
- Allergy to class/drug
- PKU
Adverse Reactions
Serious
- anaphylaxis
- seizures
- nephrotoxicity
- leukopenia or thrombocytopenia
- steven-johnson syndrome
- c-diff associated diarrhea
Common
- nausea
- diarrhea
- vomiting
- transaminitis
- dizziness
- rash
- eosinophilia
Pharmacology
- Half-life: 1.3 h
- Metabolism: other
- Excretion: urine
Mechanism of Action
bactericidal, inhibits cell wall mucopeptide synthesis
