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Cyclopentolate
From WikEM
Contents
Administration
- Type: Cycloplegic, topical anticholinergics
- Dosage Forms:
- Routes of Administration: Ophthalmic
- Common Trade Names: Cyclogyl, Cylate, Pentolair
Adult Dosing
- 1-2 drops of 0.5%-2% solution, may repeat in 5-10min if needed
Pediatric Dosing
- Small infants: 1 drop of 0.5%-2% solution
- Children: 1-2 drops of 0.5%-2% solution, may repeat with 0.5%-1% solution in 5-10min if needed
Special Populations
- Pregnancy Rating: C
- Lactation risk: infant risk cannot be ruled out
- Renal dosing
- Hepatic dosing
Contraindications
- Allergy to class/drug
- Narrow-angle glaucoma or anatomically narrow angles
Adverse Reactions
Serious
- Tachyarrythmia, vasodilation
- Seizure
- Ataxia, confusion, psychosis
- Conjunctivitis
- Raised intraocular pressure
Common
- Blurred vision
- Burning sensation in eye
- Photophobia
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
Mechanism of Action
- Anticholinergic, blocks the responses of the sphincter muscle of the iris and stimulation of ciliary body muscle, leading to cycloplegia and mydriasis.
