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Dobutamine
From WikEM
Contents
General
- Type: Vasopressors
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Dosing
- 2-20mcg/kg/min
- 10mcg works for most
- May use in peripheral IV
Rate of Titration
- Q2-5 min
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
- Tachyarrhythmias
- Myocardial ischemia
- Hypotensionas β2 effect may result in vasodilation
- Caution if SBP <90
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
Primary Receptor
- β1
- β2
Relative Effects
- ↑↑↑SV
- ↑↑HR
- ↓SVR (transient, from β2 agonism)
Notes
Indications
- Cardiogenic shock
- Low-output heart failure
- Tricyclic overdose
