We need you! Join our contributor community and become a WikEM editor through our open and transparent promotion process.
Docusate
From WikEM
Contents
Administration
- Type: stool softener; laxitive
- Dosage Forms:
- Routes of Administration: Oral, rectal
- Common Trade Names: Colace
Adult Dosing
- 50 to 200mg daily or in 2-4 divided doses
Pediatric Dosing
- <3y: 10 to 40mg/day in 1-4 divided doses
- 3-6y: 20 to 60mg/day in 1-4 divided doses
- 6-12y: 40 to 120mg/day in 1-4 divided doses
Special Populations
- Pregnancy Rating: A
- Lactation risk: Infant risk cannot be ruled out
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
- Acute obstruction
- Acute abdominal pain, vomiting
- concurrent use of mineral oil
Adverse Reactions
Serious
- Hepatotoxicity (Rare)
Common
- Diarrhea, nausea, cramping
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
Mechanism of Action
- Draws water into stool
