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Flunitrazepam toxicity
From WikEM
Contents
Background
- Also known as Rohypnol
- Used in Europe and Asia for Insomnia and Pre-op sedation
- Used in US as "date-rape" agent
- An intermediate acting benzodiazepine
- Has strong affinity for benzodiazepine receptor
Clinical Features
- CNS depression within 30 minutes
- Patients can usually be aroused with noxious stimuli
- Half life 16-35 hours but coma can last 48h
Differential Diagnosis
Sedative/hypnotic toxicity
- Toxic alcohols
- Benzodiazepines
- Flunitrazepam (Rohypnol)
- Gamma hydroxybutyrate (GHB)
- Barbiturates
- Opioids
- Chloral hydrate
- Absinthe
