Formulas

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Cardiovascular

  • O2 content = (Hb x 1.34 x SaO2) + (PaO2 x 0.003)

Pulmonary

  • Alveolar-arterial O2 gradient, pATM at sea level 760 mmHg
    • PAO2 - paO2
    • A-a O2 gradient = [FiO2 x (pATM - pH2O)] - (paCO2/0.8) - paO2
    • =[FiO2 x (760 - 47)] - (paCO2/0.8) - paO2
    • Normal for young adult non-smoker < 15 mmHg at sea level at RA
    • Normal estimate by age < (age/4) + 4[1]

References

  1. Nickson C. Lifeinthefastlane. A-a gradient. http://lifeinthefastlane.com/ccc/a-a-gradient/.