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Grey baby syndrome
From WikEM
Contents
Background
- A side effect of chloramphenicol affecting newborns of mothers who have been exposed to the drug
- Thought to be related to insufficient ability of the newborn's liver to metabolize the drug, as well as insufficient renal excretion
Clinical Features
- Symptoms usually occur within 1 week of exposure and include:
- Ashen gray color of the skin
- Failure to thrive
- Poor appetite
- Vomiting
- Hypotension
- Hypothermia
