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Ibutilide
From WikEM
Contents
General
- Type: Antiarrhythmics
- Dosage Forms:
- Common Trade Names:
Adult Dosing
- Loading dose = 1mg IV in 50mL D5W over 10min (wt>60kg)
- Loading dose = 0.01mg/kg IV in 50mL D5W over 10min (wt<60kg)
- Dose may be repeated 10min after completion of 1st dose
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation risk:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Indications
- Rapid conversion of recent-onset A-fib/flutter to NSR
Contraindications
- Allergy to class/drug
Adverse Reactions
- QT prolongation, V-tach, torsades
- Observe for 4hr after infusion
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: Class III - Prolongs AP and refractory period
Kinetics
- Onset of action = 20-30min
- Duration of action = 24hr
