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Leukemia
From WikEM
Contents
Types of Leukemia
- Acute myeloid leukemia
- Chronic myeloid leukemia
- Acute lymphocytic leukemia
- Chronic lymphocytic leukemia
- Leukemia (peds)
Differential Diagnosis
Leukocytosis
- Normally responding bone marrow
- Infection
- Inflammation: tissue necrosis, infarction, burns, arthritis
- Stress: overexertion, seizures, anxiety, anesthesia
- Drugs: corticosteroids, lithium, beta agonists
- Trauma: splenectomy
- Hemolytic anemia
- Leukemoid malignancy
- Abnormal bone marrow
Workup Consideration
- CXR
- CBC with peripheral smear
- Chem7, ca, mg, phos, Uric Acid, UA, LDH (to check for Tumor Lysis)
- LFTs, Coags, FDP, D-Dimer, Haptoglobin, Fibrinogen (to check for DIC)
- ESR, CRP
- Reticulocyte count in anemia
- Get extra purple top for flow cytometry, especially before transfusion
