We need you! Join our contributor community and become a WikEM editor through our open and transparent promotion process.
Norco
From WikEM
Contents
General
- Type: opioid
- Dosage Forms: PO
- Common Trade Names: Hydrocodone/Acetaminophen
Adult Dosing
General
Pain:
- 2.5-10mg hydrocodone/325mg Acetaminophen PO q4-6h
Pediatric Dosing
Not Currently recommended
Special Populations
- Pregnancy Rating: C
- Lactation Risk Categories: possibly unsafe
- Renal Dosing
- Adult: none
- Pediatric: none
- Hepatic Dosing
- Adult: not defined
- Pediatric: not defined
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Respiratory Depression
- Apnea
- syncope
- bradycardia
- Seizures
- anaphylaxis
- acetaminophen toxicity
Common
- Nausea
- Rash
- Headache
- Fatigue
- xerostomia
- constipation
- Tremor
- transaminitis
Pharmacology
- Half-life: 4-5 hour
- Metabolism: Liver
- Excretion: urine
- Mechanism of Action:binds to various opioid receptors