Pepper spray

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Background

Pepper (oleoresin capsicum) spray is a commonly used riot-control and violence suppressive agent. It was first used by Federal Bureau of Investigation personnel in the US in 1973.[1] The majority of the uses do not cause life threatening clinical effects. Commonly encountered effects include conjunctivitis, blepharospasm, and self induced corneal abrasions. Early decontamination minimizes the irritant effects.[2]

Active Ingredients

Oleoresin capsicum (OC) is the main active ingredient and is extracted from the genus of the plant Capsicum annuum. The five capsaicinoids include:

  1. Capsaicin
  2. Dihydrocapsaicin
  3. Nordihydrocapsaicin
  4. homocapsaicin
  5. Homodihydrocapsaicin

Capsaicin and dihydrocapsaicin constitute 80-90% of pepper spray[3]

Death Associated with Pepper Spray

  • A Patient with excited delirium, placed in physical restraint (handcuffed in prone position) with a history of chronic bronchitis experienced asphyxia due to bronchospasm[4]

Clinical Features

  • Painful burning sensation on skin
  • Involuntary eye closure
  • Decreased hand eye coordination
  • Lacrimation
  • Blepharospasm
  • Conjunctival injection
  • Cough
  • Shortness of Breath
  • Throat pain

Differential Diagnosis

Medical Conditions

Chemical weapons

Evaluation

Evaluation is focused on the irritated bodily area which is usually the eyes, throat, and skin, and lungs.[5]

Ophthalmologic

  • Assess for corneal abrasions (approx 7% incidence) and blepharitis
    • Patients may have decreased corneal sensation from 10 min after exposure to up to 1-2 hours and should be instructed to wear sunglasses or eyeware for protection.[6]

Pulmonary

  • Patients with underlying respiratory disease such as COPD and asthma may experience shortness of breath or wheezing. To evaluation for Chemical pneumonitis a chest X-ray may be useful.
  • Bronchoconstriction can be improved with inhaled beta-2 agonists such s albuterol

ENT

  • Nasal and pharyngeal erythema and irritation will resolve quickly after decontamination
  • Laryngospasm lasting up to 45 seconds has been described[7]

Dermatologic

  • Patients may experience transient dermatitis and allodynia which will self resolve[8]

Management

Treatment should be consistent with any specific injuries that are identified. Injuries that require treatment are generally only:

Ophthalmologic

Pulmonary

  • Patients with evidence of wheezing and bronchospasm may benefit from albuterol therapy

ENT

  • Most pharyngitis and mucosal irritation will self resolve

Dermatologic

  • Cool water exposure to any irritated or erythematous areas may help reduce cutaneous pain.

Disposition

Patients can generally be discharged. Only those with severe respiratory complaints may require a longer observation period in the Emergency Department

See Also

External Links

References

  1. ↑ Object of Interest: Pepper Spray. The New Yorker http://www.newyorker.com/tech/elements/object-of-interest-pepper-spray
  2. ↑ Yeung MF, William YM. Clinicopathological effects of pepper (oleoresin capsicum) spray. Hong Kong Med Journal 21(6). 2015
  3. ↑ Reilly CA, Crouch DJ, Yost GS, Fatah AA. Determination of capsaicin, dihydrocapsaicin, and nonivamide in selfdefense weapons by liquid chromatography–mass spectrometry and liquid chromatography–tandem mass spectrometry. J Chromatogr A 2001;912:259-67.
  4. ↑ Steffee CH et al. Oleoresin capsicum (pepper) spray and “in-custody deaths.” Am J Forensic Med Pathol 1995;16:185-92.
  5. ↑ Zollman TM, Bragg RM, Harrison DA. Clinical effects of oleoresin capsicum (pepper spray) on the human cornea and conjunctiva. Ophthalmology 2000;107:2186-9.
  6. ↑ Epstein RJ, Majmudar PA. Pepper spray in the eye. Ophthalmology 2001;108:1712-3.
  7. ↑ Smith CG, Stopford W. Health hazards of pepper spray. Available from: http://duketox.mc.duke.edu/pepper%20 spray.pdf. Accessed 1 Dec 2014.
  8. ↑ Kennedy WR, Vanhove GF, Lu SP, et al. A randomized, controlled, open-label study of the long-term effects of NGX-4010, a high-concentration capsaicin patch, on epidermal nerve fiber density and sensory function in healthy volunteers. J Pain 2010;11:579-87.