Physostigmine

From WikEM
Jump to: navigation, search

General

Adult Dosing

Anticholinergic toxicity

  • 0.5-2mg IV over 5min

Pediatric Dosing

  • .02mg/kg repeat every 5-10 minutes until adequate response, max of 2mg
  • no faster than .5mg/min

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

  • Side effects: bradycardia, dysrhythmias, cholinergic excess
    • Always have atropine at the bedside for bradycardia or cholinergic excess

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:
  • Onset of action: 15-20min

See Also

References