We need you! Join our contributor community and become a WikEM editor through our open and transparent promotion process.
Rifaximin
From WikEM
Contents
Administration
- Type: Antibiotic
- Dosage Forms: 200, 550
- Routes of Administration: Oral
- Common Trade Names: Xifaxan
Adult Dosing
- Traveler's diarrhea, E. coli-induced: 200mg PO tid x3 days
- Hepatic encephalopathy: 550mg PO bid
- IBS, diarrhea-predominant: 550mg PO tid x14 days
- May repeat dose up to 2x if recurrent disease
Pediatric Dosing
For > 12 yrs old
- Traveler's diarrhea, E. coli-induced: 200mg PO tid x3 days
Special Populations
- Pregnancy Rating: C
- Lactation risk: Infant risk cannot be ruled out
Renal Dosing
- No adjustment
Hepatic Dosing
- No adjustment
Contraindications
- Allergy to class/drug
- caution if hepatic impairment (Child-Pugh Class C)
- caution if recent antibiotic-associated colitis
Adverse Reactions
Serious
- superinfection
- C. difficile-assoc. diarrhea
- hypersensitivity reaction
- angioedema
- anaphylaxis
- exfoliative dermatitis
Common
- peripheral edema
- nausea
- dizziness
- fatigue
Comments
See Also
References
<Epocrates, UpToDate>
