STOPP/START criteria

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Background

  • Guideline for appropriateness of use of medications in the elderly
  • Developed to address deficiencies of Beers criteria[1]
  • STOPP criteria medications are significantly associated with adverse drug events (ADEs), unlike Beers criteria medications [2].
  • STOPP/START criteria as an intervention applied at a single time point during hospitalization for acute illness in older people significantly improve medication appropriateness, an effect that is maintained 6 months post-intervention[3]
  • STOPP/START criteria as an intervention applied within 72 h of admission significantly reduce adverse drug reactions (ADRs)
    • With an absolute risk reduction of 9.3%
    • Number needed to treat = 11
    • Average length of stay of 3 days in older people hospitalized with acute illnesses[4]

See Also

External Links

STOPP/START criteria for potentially inappropriate prescribing in older people: version 2

References

  1. O'Mahony D ; O'Sullivan D ; Byrne S; et al. STOPP/START criteria for potentially inappropriate prescribing in older people: version 2. Age Ageing. 2015; 44: 213-218
  2. Hamilton H, Gallagher P, Ryan C, Byrne S, O'Mahony D. Potentially inappropriate medications defined by STOPP criteria and the risk of adverse drug events in older hospitalized patients. Arch Intern Med 2011;171:1013-
  3. Gallagher PF, O'Connor MN, O'Mahony D. Prevention of potentially inappropriate prescribing for elderly patients: a randomized controlled trial using STOPP/START criteria. Clin Pharmacol Ther 2011;89:845-54
  4. O'Connor MN. University College Cork; 2013. Adverse Drug Reactions in Older People During Hospitalisation: Prevalence, Risk factors and Recognition. Unpublished MD thesis. https://www.clinicaltrials.gov/ct2/show/study/NCT01467050

Authors

Amr Badawy