Staphylococcus epidermidis

Background

Staphylococcus epidermidis is a coagulase-negative staphylococcus, a gram-positive bacteria

Category	Antibiotic	Staph. Epidermidis
Penicillins	Penicillin G	R
	Penicillin V	R
	Methicillin	S
	Nafcillin/Oxacillin	S
	Cloxacillin/Diclox.	S
Amino-Penicillins	AMP/Amox	R
	Amox-Clav	R
	AMP-Sulb	R
Anti-Pseudomonal Penicillins	Ticarcillin	I
	Ticar-Clav	I
	Pip-Tazo	S
	Piperacillin	R
Carbapenems	Doripenem	S
	Ertapenem	S
	Imipenem	S
	Meropenem	S
	Aztreonam	R
Fluroquinolones	Ciprofloxacin	S
	Ofloxacin	S
	Pefloxacin	S
	Levofloxacin	S
	Moxifloxacin	S
	Gemifloxacin	S
	Gatifloxacin	S
1st G Cephalo	Cefazolin	I
2nd G. Cephalo	Cefotetan	I
	Cefoxitin	I
	Cefuroxime	I
3rd/4th G. Cephalo	Cefotaxime	I
	Cefizoxime	I
	CefTRIAXone	I
	Ceftaroline	S
	CefTAZidime	I
	Cefepime	I
Oral 1st G. Cephalo	Cefadroxil	I
	Cephalexin	I
Oral 2nd G. Cephalo	Cefaclor/Loracarbef	I
	Cefproxil	I
	Cefuroxime axetil	I
Oral 3rd G. Cephalo	Cefixime	R
	Ceftibuten	R
	Cefpodox/Cefdinir/Cefditoren	I
Aminoglycosides	Gentamicin	I
	Tobramycin	I
	Amikacin	I
	Chloramphenicol	R
	Clindamycin	R
Macrolides	Erythromycin	I
	Azithromycin	R
	Clarithromycin	R
Ketolide	Telithromycin	R
Tetracyclines	Doxycycline	R
	Minocycline	R
Glycylcycline	Tigecycline	S
	Daptomycin	S
Glyco/Lipoclycopeptides	Vancomycin	S
	Teicoplanin	I
	Telavancin	S
	Fusidic Acid	S
	Trimethoprim	S
	TMP-SMX	I
Urinary Agents	Nitrofurantoin	X1
	Fosfomycin	X1
Other	Rifampin	S
	Metronidazole	R
	Quinupristin dalfoppristin	S
	Linezolid	S
	Colistimethate	R

S susceptible/sensitive (usually)
I intermediate (variably susceptible/resistant)
R resistant (or not effective clinically)
S+ synergistic with cell wall antibiotics
U sensitive for UTI only (non systemic infection)
X1 no data
X2 active in vitro, but not used clinically
X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
X4 active in vitro, but not clinically effective for strep pneumonia