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Streptococcus pneumoniae
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(Redirected from Strep pneumoniae)
Contents
Background
- Gram Positive cocci in clusters/pairs
- Asociated with pneumonia, meningitis, peritonitis and other severe infections
- Isolation of this organism is always significant and should be treated[1]
Antibiotic Sensitivities[2]
Category | Antibiotic | Strep. Pneumoniae |
Penicillins | Penicillin G | S |
Penicillin V | S | |
Methicillin | S | |
Nafcillin/Oxacillin | S | |
Cloxacillin/Diclox. | S | |
Amino-Penicillins | AMP/Amox | S |
Amox-Clav | S | |
AMP-Sulb | S | |
Anti-Pseudomonal Penicillins | Ticarcillin | S |
Ticar-Clav | S | |
Pip-Tazo | S | |
Piperacillin | S | |
Carbapenems | Doripenem | S |
Ertapenem | S | |
Imipenem | S | |
Meropenem | S | |
Aztreonam | R | |
Fluroquinolones | Ciprofloxacin | I |
Ofloxacin | I | |
Pefloxacin | R | |
Levofloxacin | S | |
Moxifloxacin | S | |
Gemifloxacin | S | |
Gatifloxacin | S | |
1st G Cephalo | Cefazolin | S |
2nd G. Cephalo | Cefotetan | S |
Cefoxitin | S | |
Cefuroxime | S | |
3rd/4th G. Cephalo | Cefotaxime | S |
Cefizoxime | S | |
CefTRIAXone | S | |
Ceftaroline | S | |
CefTAZidime | S | |
Cefepime | S | |
Oral 1st G. Cephalo | Cefadroxil | S |
Cephalexin | S | |
Oral 2nd G. Cephalo | Cefaclor/Loracarbef | S |
Cefproxil | S | |
Cefuroxime axetil | S | |
Oral 3rd G. Cephalo | Cefixime | S |
Ceftibuten | I | |
Cefpodox/Cefdinir/Cefditoren | S | |
Aminoglycosides | Gentamicin | R |
Tobramycin | R | |
Amikacin | R | |
Chloramphenicol | S | |
Clindamycin | S | |
Macrolides | Erythromycin | I |
Azithromycin | I | |
Clarithromycin | I | |
Ketolide | Telithromycin | S |
Tetracyclines | Doxycycline | S |
Minocycline | S | |
Glycylcycline | Tigecycline | S |
Daptomycin | X4 | |
Glyco/Lipoclycopeptides | Vancomycin | S |
Teicoplanin | S | |
Telavancin | S | |
Fusidic Acid | I | |
Trimethoprim | I | |
TMP-SMX | S | |
Urinary Agents | Nitrofurantoin | S |
Fosfomycin | S | |
Other | Rifampin | S |
Metronidazole | R | |
Quinupristin dalfoppristin | S | |
Linezolid | S | |
Colistimethate | R |
Key
- S susceptible/sensitive (usually)
- I intermediate (variably susceptible/resistant)
- R resistant (or not effective clinically)
- S+ synergistic with cell wall antibiotics
- U sensitive for UTI only (non systemic infection)
- X1 no data
- X2 active in vitro, but not used clinically
- X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
- X4 active in vitro, but not clinically effective for strep pneumonia
Table Overview
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See Also
References
- ↑ Antibiotic Therapy for Positive Blood Cultures. Perez-Jorge EV, et al. Antimicrobe. http://www.antimicrobe.org/new/e38rev2.asp
- ↑ Sanford Guide to Antimicrobial Therapy 2014