Template:Neonatal conjunctivitis treatment

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Prophylaxis

Erythromycin 0.5% ointment x1 or Tetracycline 1% or Silver Nitrate 1% x1 topical, applied at birth.

Chemical

  • Watchful waiting

Gonococcal (onset 2-4 days)

  • Cefotaxime 100mg/kg IV or IM OR ceftriaxone 25-50mg/kg IV or IM x1 (not to exceed 125mg)
    • Cefotaxime is preferred because it does not displace bilirubin
    • Disseminated disease should be suspected until CSF is negative
    • Treat mother and partners
    • Irrigate eyes with saline (topical antibiotics are insufficient and unnecessary)

Chlamydia (onset 3-10 days)

  • Azithromycin 20mg/kg PO once daily x 3 days OR
  • Erythromycin 50mg/kg PO QD in 4 divided doses x 14 days
    • Disease manifests 5 days post-birth to 2 weeks (late onset)
  • Topical treatment is unnecessary

Herpetic (onset 6-14 days)

  • Acyclovir 20mg/kg IV q8hr x 14-21d
  • Topical antiviral
  • Full neonatal sepsis evaluation
  • Immediate ophtho consult