Triamcinolone acetonide

Administration

• Type: Topical steroids
• Dosage Forms: Ointment/Cream: 0.025%, 0.5% . Nasal spray: 55 mcg/spray
• Routes of Administration: Topical, intranasal
• Common Trade Names: Kenalog, Aristocort cream, Nasocort

Adult Dosing

• Skin disorders
  • Apply to affected areas 2-4 times per day
• Allergic rhinitis
  • 2 sprays in each nostril 1-2 times per day

Pediatric Dosing

• Topical: apply to affected area 2-4 times per day
• Intranasal:
  • 6-12yo: 1 spray in each nostril 1-2 times per day
  • 2-5yo: 1 spray in each nostril once daily

Special Populations

• Pregnancy Rating: C
• Lactation risk: Infant risk cannot be ruled out

Renal Dosing

• Adult:
• Pediatric:

Hepatic Dosing

• Adult:
• Pediatric:

Contraindications

• Allergy to class/drug
• Avoid applying to groin or open skin

Adverse Reactions

Serious

• Secondary hypocortisolism (Very rare with topicals, only with prolonged use of high-potency ointment over large areas)

Common

• No truly "common" adverse reaction for topical/intranasal forms, but may

Pharmacology

• Absorption: Percutaneous absorption: bioavailability 1-7% for areas excluding groin. Intranasal bioavailability minimal
• Half-life:
• Metabolism:
• Excretion:

Mechanism of Action

• Adrenal glucocorticoid

See Also

• Topical steroids

References

Authors

Claire, Ross Donaldson, Frank Johnston