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Valacyclovir
From WikEM
Contents
General
- Type: Antiviral, inhibits DNA polymerase
- Dosage Forms: 500, 1000
- Common Trade Names: Valtrex
Adult Dosing
HSV-1
- Acute episode: 2000mg PO BID x 1 day
- Suppression: 500mg PO Qday
Genital HSV
- 1st episode: 1000mg PO BID x 7-10 days, start within 48-72 hour of symptoms
- recurrence: 500mg PO BID x 3 days, alternative: 1000mg PO qday x 5 days
Shingles
- 1000mg PO TID x 7 days
Pediatric Dosing
Genital HSV
- ≥12 yrs same as adult dosing for adolescents
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
