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Vitamin E deficiency
From WikEM
Contents
Background
- Most common causes:
- Severe malabsorption (eg, cystic fibrosis)
- Abetalipoproteinemia (genetic disorder)
- Chronic cholestatic liver disease (e.g. biliary atresia)
Clinical Features
- Areflexia
- Gait disturbance
- Decreased vibration and proprioception
- Ophthalmoplegia
Differential Diagnosis
Evaluation
- Plasma Vitamin E level <0.5 mg/dL
Management
- Vitamin E repletion
