FAM82A* Allele and Genotype Frequencies
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This website is archived for historical purposes and is no longer being maintained or updated.
Available polymorphism(s)
|
rs number |
Common Designations Nucleotide change Amino acid |
Genotyping method |
|
|---|---|---|---|
|
rs163086 |
IVS10-1363C>T |
TaqMan |
|
* FAM82A is a hypothetical protein that lies immediately 5′ of CYP1B1. This variant may be an intronic polymorphism of FAM82A or a CYP1B1 variant that lies 3’ of the gene
By Race/Ethnicity
| Variant | Race-ethnicity | Allele % (95% CI) |
Chi-square P-value† |
Genotype % (95% CI) |
Chi-square P-value† |
HW P-value‡ |
|||
|---|---|---|---|---|---|---|---|---|---|
| rs163086 | C | T | CC | CT | TT | ||||
| Non-Hispanic White | 77.2 (75.5, 78.8) | 22.8 (21.2, 24.5) | <0.001 | 59.8 (57.0, 62.6) | 34.7 (32.0, 37.5) | 5.5 (4.3, 6.9) | <0.001 | 0.73 | |
| Non-Hispanic Black | 80.9 (79.0, 82.6) | 19.1 (17.4, 21.0) | 65.0 (62.1, 67.8) | 31.7 (29.3, 34.2) | 3.3 (2.3, 4.6) | 0.18 | |||
| Mexican American | 85.5 (83.7, 87.0) | 14.5 (13.0, 16.3) | 73.4 (70.6, 76.0) | 24.1 (21.9, 26.4) | 2.5 (1.8, 3.4) | 0.18 | |||
| Total* | 78.7 (77.4, 80.0) | 21.3 (20.0, 22.6) | 62.3 (60.2, 64.2) | 32.9 (31.2, 34.8) | 4.8 (3.9, 5.9) | ||||
* Includes all U.S. race/ethnic groups.
† “other” race/ethnicity category was not included in chi-square tests.
‡ P-values from unweighted chi-square goodness-of-fit tests to test for deviations from Hardy-Weinberg (HW) proportions.
By Age*
| Variant | Age (years) | Allele % (95% CI) |
Chi-square P-value |
Genotype % (95% CI) |
Chi-square P-value |
|||
|---|---|---|---|---|---|---|---|---|
| rs163086 | C | T | CC | CT | TT | |||
| 12-19 | 74.7 (70.2, 78.6) | 25.3 (21.4, 29.8) | 0.035 | 56.0 (49.7, 62.2) | 37.2 (32.6, 42.0) | 6.7 (4.5, 9.9) | 0.036 | |
| 20-39 | 78.7 (76.9, 80.5) | 21.3 (19.5, 23.1) | 62.4 (59.2, 65.5) | 32.6 (29.6, 35.8) | 5.0 (3.9, 6.3) | |||
| 40-59 | 79.1 (76.3, 81.6) | 20.9 (18.4, 23.7) | 62.6 (58.4, 66.6) | 33.0 (29.6, 36.5) | 4.5 (3.0, 6.6) | |||
| >=60 | 81.1 (79.3, 82.9) | 18.9 (17.1, 20.7) | 65.9 (63.0, 68.7) | 30.4 (27.7, 33.2) | 3.7 (2.5, 5.4) | |||
| Total | 78.7 (77.4, 80.0) | 21.3 (20.0, 22.6) | 62.3 (60.2, 64.2) | 32.9 (31.2, 34.8) | 4.8 (3.9, 5.9) | |||
* Includes all participants, regardless of race/ethnicity.
By Sex*
| Variant | Sex | Allele % (95% CI) |
Chi-square P-value |
Genotype % (95% CI) |
Chi-square P-value |
|||
|---|---|---|---|---|---|---|---|---|
| rs163086 | C | T | CC | CT | TT | |||
| Male | 78.5 (76.4, 80.5) | 21.5 (19.5, 23.6) | 0.826 | 61.6 (58.4, 64.8) | 33.8 (30.8, 36.9) | 4.6 (3.1, 6.6) | 0.615 | |
| Female | 78.9 (76.9, 80.8) | 21.1 (19.2, 23.1) | 62.8 (60.1, 65.5) | 32.1 (30.1, 34.3) | 5.1 (3.7, 6.9) | |||
| Total | 78.7 (77.4, 80.0) | 21.3 (20.0, 22.6) | 62.3 (60.2, 64.2) | 32.9 (31.2, 34.8) | 4.8 (3.9, 5.9) | |||
* Includes all participants, regardless of race/ethnicity.
By Race/Ethnicity and Age
| Variant | Race-ethnicity | Age (years) | Allele % (95% CI) |
Genotype % (95% CI) |
|||
|---|---|---|---|---|---|---|---|
| rs163086 | C | T | CC | CT | TT | ||
| Non-Hispanic White | 12-19 | 72.1 (65.7, 77.6) | 27.9 (22.4, 34.3) | 53.3 (44.5, 61.9) | 37.6 (31.3, 44.3) | 9.2 (5.9, 14.0) | |
| 20-39 | 76.8 (73.9, 79.5) | 23.2 (20.5, 26.1) | 59.3 (54.5, 63.9) | 35.1 (30.6, 39.8) | 5.6 (3.9, 8.0) | ||
| 40-59 | 77.5 (74.0, 80.6) | 22.5 (19.4, 26.0) | 59.7 (54.2, 65.0) | 35.5 (30.7, 40.6) | 4.8 (3.0, 7.4) | ||
| >=60 | 80.3 (78.0, 82.4) | 19.7 (17.6, 22.0) | 64.6 (61.2, 67.8) | 31.4 (28.6, 34.4) | 4.0 (2.6, 6.1) | ||
| Non-Hispanic Black | 12-19 | 78.5 (75.0, 81.6) | 21.5 (18.4, 25.0) | 60.7 (54.9, 66.3) | 35.4 (30.2, 41.1) | 3.8 (2.2, 6.6) | |
| 20-39 | 81.3 (78.5, 83.8) | 18.7 (16.2, 21.5) | 65.5 (60.8, 69.9) | 31.6 (27.3, 36.2) | 2.9 (1.6, 5.3) | ||
| 40-59 | 80.7 (78.7, 82.7) | 19.3 (17.3, 21.3) | 65.6 (62.7, 68.3) | 30.3 (27.3, 33.6) | 4.1 (2.4, 7.0) | ||
| >=60 | 83.1 (79.5, 86.2) | 16.9 (13.8, 20.5) | 68.3 (61.2, 74.6) | 29.7 (22.9, 37.4) | 2.1 (0.8, 5.5) | ||
| Mexican American | 12-19 | 86.3 (82.7, 89.4) | 13.7 (10.6, 17.3) | 74.6 (68.1, 80.1) | 23.5 (18.4, 29.5) | 1.9 (1.0, 3.5) | |
| 20-39 | 85.0 (83.2, 86.7) | 15.0 (13.3, 16.8) | 73.1 (70.3, 75.7) | 23.9 (21.7, 26.3) | 3.0 (2.0, 4.4) | ||
| 40-59 | 86.0 (84.1, 87.7) | 14.0 (12.3, 15.9) | 74.0 (69.4, 78.1) | 24.0 (19.1, 29.6) | 2.0 (1.1, 3.6) | ||
| >=60 | 84.5 (79.8, 88.3) | 15.5 (11.7, 20.2) | 71.3 (63.4, 78.1) | 26.5 (20.5, 33.5) | 2.2 (1.2, 4.3) | ||
By Race/Ethnicity and Sex
| Variant | Race-ethnicity | Sex | Allele % (95% CI) |
Genotype % (95% CI) |
|||
|---|---|---|---|---|---|---|---|
| rs163086 | C | T | CC | CT | TT | ||
| Non-Hispanic White | Male | 76.8 (74.3, 79.2) | 23.2 (20.8, 25.7) | 58.8 (54.7, 62.8) | 36.0 (32.1, 40.2) | 5.1 (3.5, 7.5) | |
| Female | 77.5 (74.9, 79.9) | 22.5 (20.1, 25.1) | 60.8 (57.3, 64.1) | 33.5 (30.8, 36.2) | 5.7 (3.9, 8.4) | ||
| Non-Hispanic Black | Male | 80.5 (78.3, 82.5) | 19.5 (17.5, 21.7) | 64.5 (61.0, 67.8) | 32.0 (29.0, 35.2) | 3.5 (2.3, 5.3) | |
| Female | 81.2 (78.4, 83.7) | 18.8 (16.3, 21.6) | 65.5 (61.0, 69.7) | 31.4 (27.9, 35.3) | 3.1 (2.0, 4.7) | ||
| Mexican American | Male | 84.9 (82.0, 87.4) | 15.1 (12.6, 18.0) | 72.2 (67.1, 76.8) | 25.3 (21.1, 30.0) | 2.5 (1.9, 3.2) | |
| Female | 86.1 (84.6, 87.4) | 13.9 (12.6, 15.4) | 74.7 (71.9, 77.3) | 22.8 (19.9, 25.9) | 2.5 (1.6, 4.0) | ||
- Page last reviewed: March 16, 2009 (archived document)
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