1993 Revised Classification System for HIV Infection and Expanded
Surveillance Case Definition for AIDS Among Adolescents and Adults
On December 18, 1992, CDC published a revised classification
system for human immunodeficiency virus (HIV) infection and an
expanded surveillance case definition for acquired immunodeficiency
syndrome (AIDS) among adolescents and adults in the United States
(1). * Based on the clinical standard for immunologic monitoring of
persons infected with HIV, the revised HIV classification system
includes the CD4+ T-lymphocyte measurement in the categorization of
HIV-related clinical conditions and replaces the HIV classification
system published in 1986 (2). In addition, the expanded AIDS
surveillance case definition includes all HIV-infected persons who
have less than 200 CD4+ T-lymphocytes/uL or a CD4+ T-lymphocyte
percent of total lymphocytes less than 14, or who have been
diagnosed with pulmonary tuberculosis, invasive cervical cancer, or
recurrent pneumonia. The new AIDS surveillance case definition
retains the reporting criteria listed in the 1987 AIDS surveillance
case definition (3). The objectives of the expansion are to reflect
more accurately the number of persons with severe HIV-related
morbidity and immunosuppression and to simplify the reporting
process. Beginning January 1, 1993, this expanded AIDS surveillance
case definition is to be used by all states and territories for
AIDS case reporting.
Single copies of the document will be available in mid-January
from the CDC National AIDS Clearinghouse, P.O. Box 6003, Rockville,
MD 20849-6003; telephone (800) 458-5231.
References
CDC. 1993 Revised classification system for HIV infection and
expanded surveillance case definition for AIDS among adolescents
and adults. MMWR 1992;41(no. RR-17).
CDC. Classification system for human T-lymphotropic virus type
III/lymphadenopathy-associated virus infections. MMWR 1986;35:334-
CDC. Revision of the CDC surveillance case definition for
acquired immunodeficiency syndrome. MMWR 1987;36(no. S-1).
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