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Nicotine

Synonyms & Trade Names
3-(1-Methyl-2-pyrrolidyl)pyridine
CAS No.
54-11-5
RTECS No.
QS5250000
DOT ID & Guide
1654 151
Formula
C₅H₄NC₄H₇NCH₃
Conversion
IDLH
5 mg/m3
See: 54115
Exposure Limits
NIOSH REL
TWA 0.5 mg/m3 [skin]
OSHA PEL
TWA 0.5 mg/m3 [skin]
Measurement Methods
NIOSH 2544 , 2551
See: NMAM or OSHA Methods
Physical Description
Pale-yellow to dark-brown liquid with a fish-like odor when warm. [insecticide]
Molecular Weight
162.2
Boiling Point
482°F (Decomposes)
Freezing Point
-110°F
Solubility
Miscible
Vapor Pressure
0.08 mmHg
Ionization Potential
8.01 eV
Specific Gravity
1.01
Flash Point
203°F
Upper Exposive Limit
4.0%
Lower Explosive Limit
0.7%
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Incompatibilities & Reactivities
Strong oxidizers, strong acids
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
nausea, salivation, abdominal pain, vomiting, diarrhea; headache, dizziness, hearing, visual disturbance; confusion, lassitude (weakness, exhaustion), incoordination; cardiac arrhythmias; convulsions, dyspnea (breathing difficulty); In Animals: teratogenic effects
Target Organs
central nervous system, cardiovascular system, lungs, gastrointestinal tract, reproductive system
Personal Protection/Sanitation
(See protection codes)
Skin:Prevent skin contact
Eyes:Prevent eye contact
Wash skin:When contaminated
Remove:When wet or contaminated
Change:No recommendation
Provide:Eyewash, Quick drench
First Aid
(See procedures)
Eye:Irrigate immediately
Skin:Water flush immediately
Breathing:Respiratory support
Swallow:Medical attention immediately
Respirator Recommendations

NIOSH/OSHA

Up to 5 mg/m3:
(APF = 10) Any supplied-air respirator
(APF = 50) Any self-contained breathing apparatus with a full facepiece

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also
INTRODUCTION   ICSC CARD: 0519   MEDICAL TESTS: 0157

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