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Perioral dermatitis
From WikEM
Contents
Background
- 90% female (increasing in males)
Etiology
- Topical or inhaled steroids
- use of cosmetics,
- physical (UVB, heat, wind),
- microbiological (fusiform spirilla, candida)
- hormonal factors (premenstrual deterioration, use of oral contraceptives)
- GI tract abnormalities (malabsorption)
- emotional stress.
Clinical Features
- papular, vesiculopapular and papulopustular lesions on erythematous base (Acneiform)
- confluent aspect, follicular
- location perioral, limited to skin
- typically respects rim around and 3-5 mm under lower lip, circular
Differential Diagnosis
- Rosacea
- Seborrheic Dermatitis
- Acne vulgaris
- Facial demodicosis
- Lupus milliaris
- Polymorphous light reaction
- Contact dermatitis
- Haber syndrome
- Granulomatous periorificial dermatitis
Oral rashes and lesions
- Angioedema
- Aphthous stomatitis
- Herpes gingivostomatitis
- Herpes labialis
- Measles (Koplik's spots)
- Perioral dermatitis
- Oral thrush
- Steven Johnson syndrome
- Strep pharyngitis
Evaluation
- Usually clinical
Management
- Discontinue suspected topicals
- Rebound reaction
- hydrocortisone cuts down reaction violence
- Corticosteroid dependence - psychological follow up
- Suppression of follicular bacterial infection
- Lipophilic tetracyclines 100-250mg/d for 3-4 months
- no response - Isotretinoin
- Children - oral, topical Erythromycin, Metronidazole
- Antipruritics containing no corticosteroids
Complications
- Disfiguring scars - emotional
- Rebound effect, chronic course
- Lupus-like PD - dermal infiltrate, scarring
- Yellowish discoloration after diascopy
See Also
References
- Ljubojević et al. "Perioral dermatitis" Acta Dermatovenerol Croat. 2008;16(2):96-100
