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Smallpox
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About CDC.gov
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Smallpox
About Smallpox
History of Smallpox
Spread and Eradication of Smallpox
Transmission
Signs and Symptoms
Prevention and Treatment
Smallpox Vaccine Basics
Vaccine Safety
Side Effects of Vaccination
Who Should Get a Smallpox Vaccination?
Bioterrorism
The Threat
Preparedness
Detection and Response
Bioterrorism Response Planning
Community-Based Planning for a Smallpox Emergency
Build Community Partnerships
Identify Resources and Needs
Help People with Functional, Language, or Cognitive Needs
Public Health Response Activities
Identify, Diagnose, and Isolate Cases
Enhanced Surveillance and Case Reporting
Epidemiological Investigation
Vaccination Strategies
Ring Vaccination
Community-Wide (Mass) Vaccination
Download Maxi-Vac Version 1.0 and Maxi-Vac Alternative
Description of Maxi-Vac Programs
Differences Between Maxi-Vac Version 1 and Alternative Version
Communication
Information Management
Healthcare Facility Response Activities
Protect and Care for Smallpox Patients
Vaccinate Your Staff
Care for Your Staff
Prevent Spread of Disease
Research
For Clinicians
Transmission
Clinical Disease
Diagnosis & Evaluation
Evaluating Patients for Smallpox
Treatment
Vaccination
Vaccines
Contraindications to Vaccination
Vaccine Administration
Expected Vaccine Reactions
Vaccine “Take” Evaluation
Vaccine Adverse Events
Medical Management of Adverse Reactions
Comparison of Reactions for First-Time Vaccinees and Revaccinees
Examples of Major or “Take” Reactions to Smallpox Vaccination
Vaccine Adverse Reaction Images
Laboratory Personnel
Specimen Collection
Specimen Collection and Transport Guidelines for Suspect Smallpox Cases
Specimen Collection and Transport Guidelines for Suspect Smallpox Vaccine Adverse Events
Specimen Collection Procedures
Negative Staining Electron Microscope Protocol for Rash Illness
Packaging and Transporting Infectious Substances
Rash Illness Protocol
Chart 1: Acute, Generalized Vesicular or Pustular Rash Illness Protocol
Chart 2: Laboratory Testing for Acute, Generalized Vesicular or Pustular Rash Illness
Chart 3: Laboratory Testing for Suspect Smallpox Vaccine Adverse Event (Vaccinia)
Chart 4: Laboratory Testing for Environmental Sample
Related Links
WHO Smallpox Website
NIH Smallpox Research
CDC Poxvirus and Rabies Branch
Poxvirus Diseases
Specimen Collection
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Specimen Collection and Transport Guidelines for Suspect Smallpox Cases
Specimen Collection and Transport Guidelines for Suspect Smallpox Vaccine Adverse Events
Specimen Collection Procedures
Negative Staining Electron Microscope Protocol for Rash Illness
Related Links
WHO Smallpox Website
NIH Smallpox Research
CDC Poxvirus and Rabies Branch
Poxvirus Diseases
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Page last reviewed:
December 1, 2016
Page last updated:
December 1, 2016
Content source:
Centers for Disease Control and Prevention
National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
Division of High-Consequence Pathogens and Pathology (DHCPP)
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