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Reported Tuberculosis in the United States, 2012

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Table 10. Percentages of Tuberculosis Cases by Initial Drug Regimen, Use of Directly Observed Therapy (DOT), and Completion of Therapy (COT): United States, 1993–2012

YearInitial Drug Regimen1,2Directly Observed Therapy3Therapy ≤1 Year Indicated4
I RIRZIRZEDOT OnlyBoth DOT and Self-AdministeredCOT ≤1 YearCOT

1993

(12.9)

(31.2)

(40.3)

(21.7)

(14.4)

(64.0)

(87.5)

1994

(7.0)

(23.3)

(55.7)

(28.1)

(20.5)

(69.0)

(87.9)

1995

(5.2)

(20.3)

(62.7)

(37.3)

(21.5)

(74.0)

(89.8)

1996

(4.2)

(17.5)

(67.3)

(42.5)

(22.4)

(76.5)

(90.6)

1997

(3.2)

(15.1)

(71.9)

(47.0)

(23.8)

(78.3)

(91.4)

1998

(2.6)

(12.9)

(74.3)

(47.7)

(26.6)

(80.6)

(92.5)

1999

(2.2)

(11.2)

(76.9)

(49.4)

(27.6)

(80.8)

(92.4)

2000

(2.0)

(10.4)

(78.5)

(52.5)

(25.8)

(81.6)

(92.7)

2001

(1.7)

(9.6)

(79.8)

(53.6)

(27.5)

(81.8)

(92.8)

2002

(1.8)

(8.9)

(80.3)

(55.4)

(27.8)

(82.3)

(92.7)

2003

(1.4)

(8.1)

(81.3)

(56.5)

(28.5)

(83.0)

(92.9)

2004

(1.5)

(6.4)

(82.4)

(58.9)

(27.7)

(83.6)

(92.6)

2005

(1.3)

(5.5)

(83.7)

(57.9)

(29.6)

(83.2)

(92.6)

2006

(1.2)

(4.8)

(83.3)

(57.5)

(30.4)

(84.1)

(93.3)

2007

(1.1)

(4.6)

(83.6)

(56.3)

(32.9)

(84.8)

(94.0)

2008

(1.0)

(3.5)

(84.3)

(56.4)

(33.5)

(85.2)

(93.4)

2009

(1.0)

(3.2)

(84.2)

(59.6)

(30.3)

(87.8)

(95.5)

2010

(0.9)

(3.0)

(84.5)

(59.1)

(31.1)

(88.1)

(95.6)

20115

(0.7)

(2.7)

(85.2)

(62.7)

(28.5)

(82.1)

(88.0)

2012

(0.7)

(2.2)

(84.5)

(64.0)

(25.8)

(47.1)

(48.3)

1 Includes persons alive at diagnosis.

2 I=isoniazid; R=rifampin; Z=pyrazinamide; E=ethambutol. Excludes cases with no information on initial drug regimen; In 2012, 0.83% re-
ceived no initial drug therapy, 0.25% were started on one drug, and 11.50% had an initial multidrug regimen other than IR, IRZ, or IRZE.

3 Includes persons alive at diagnosis with initial drug regimen of one or more drugs prescribed.

4 Includes persons alive at diagnosis, with initial drug regimen of one or more drugs prescribed, who did not die during therapy. Excludes persons with initial isolate rifampin resistant, or patient with meningeal disease, or pediatric patient (aged <15) with miliary disease or positive blood culture.

5 Beginning in 2011, those who moved out of country during treatment are excluded from the denominator of those eligible for COT.

Note: Data for all years updated through June 10, 2013.

See Technical Notes for description of COT calculation.

See Surveillance Slides #30 and #31 .

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