Annual Smoking-Attributable Mortality, Years of Potential Life Lost, and Productivity Losses—United States, 1997–2001

An estimated $92 billion (average for 1997–2001) in productivity losses occurs annually from deaths due to smoking. The economic costs of smoking are more than $167 billion, including an additional $75.5 billion in smoking-related medical expenditures.
Cigarette smoking caused an estimated 438,000 premature deaths annually (259,494 men and 178,408 women) from 1997 through 2001.
Among adults, the study estimates that most deaths were from lung cancer (123,836), chronic obstructive pulmonary disease (90,582), and ischemic heart disease (86,801).
Smoking during pregnancy resulted in an estimated 523 male infant and 387 female infant deaths annually.
Smoking causes 3.3 million years of potential life lost for men and 2.2 million years for women. Smoking, on average, reduces adult life expectancy by approximately 14 years.